tx

Question 1

acute bacterial mastitis

Answer 1

antibiotics, continue expression of breast milk; rarely requires surgical drainage.

Question 2

Squamous Metaplasia of Lactiferous Ducts

• AKA: Subaerolar abscess, Periductal mastitis, or Zuska dz.

Answer 2

o Commonly recur following drainage d/t remaining keratinizing epi.
o Curative if the duct & fistula tract are surgically removed.

Question 3

Granulomatous Mastitis

Answer 3

steroids

Question 4

DCIS

Answer 4

 Surgical excision and radiation/tamoxifen = Mostly curative
 Mastectomy = Cure in 95%

Question 5

LCIS

Answer 5

 B/l prophylactic mastectomy, tamoxifen can also be done.

Question 6

ER(+), HER2(-), Low Proliferation Invasive (infiltrating) Carcinoma

Answer 6

anti-estrogen (tamoxifen); cured by sx; not respond to chemo

Question 7

ER(+), HER2(-), high Proliferation Invasive (infiltrating) Carcinoma

Answer 7

10% respond to chemo

Question 8

HER+ Invasive (infiltrating) Carcinoma

Answer 8

• 1/3 respond completely to Ab (trastuzumab) that bind & block receptor activity = excellent prognosis.
• May respond to trastuzumab or may make them resistant to all tx

Question 9

ER(-), HER2(-) Invasive (infiltrating) Carcinoma

Answer 9

30% respond well to chemo and cure is possible.

Question 10

male breast cancer

Answer 10

mastectomy and axillary LN dissection

Question 11

phyllodes tumor (cystosarcoma)

Answer 11

NOT LN dissection bc lymphatic spread rare