Tutorial - Week 4 Content Flashcards
Which of the following statements about the role of calcium in chemical synaptic transmission is TRUE?
a. calcium is required to transport the neurotransmitter across the synaptic cleft
b. calcium is required for exocytosis of the neurotransmitter
c. calcium is required for endocytosis of the neurotransmitter
d. calcium is required for neurotransmitter/receptor activation
e. calcium is responsible for the generation of an EPSP
b
Which of the following statements regarding neurotransmitters in FALSE?
a. neurotransmitter are not involved in electrical synapses
b. it is the nature of the receptor for the neurotransmitter that determines whether a synapse excitatory or inhibitory
c. it is the nature of the neurotransmitter that determines whether a synapse is excitatory or inhibitory
d. neurotransmitters are stored in vesicles in presynaptic neurones
e. neurotransmitters are released by exocytosis
c
Inhibitory post synaptic potentials can be the result of which of the following?
a. sodium channels opening
b. sodium channels closing
c. potassium channels closing
d. calcium channels closing
e. none of the above
e
A small transient INCREASE in the magnitude of the membrane potential of a nerurone at rest is known as which of the following?
a. a hyperpolarising graded potential
b. an action potential
c. a resting membrane potential
d. a depolarising graded potential
e. an equilibrium potential
a
Neurotransmitters that modify the metabolism of post-synaptic neurones have all of the following feature except ONE. Identify the EXCEPTION:
a. 2nd messenger systems that mediate their intracellular effects
b. modification of gene expression
c. upregulation of enzyme activity
d. modification of ion channel sensitivity
e.
d
Describe the mechanism by which glutamate produces an excitatory post synaptic potential
Describe the mechanism by which glutamate produces an excitatory post synaptic potential
