Tutorial 6- Dosage Calculations Flashcards
Dose
The term DOSE refers to the amount of medication
that a patient must take at one time to produce the
optimum therapeutic effect.
What are the terms “average dose”,“ usual dose,” and “adult dose” based on?
the amount of medication needed to treat the average size adult (70 kg) with optimum effect.
Dosage
Refer to the treatment plan
True or False
Dosage varies with the condition being treated.
True
True or False
Different products of the same API are present in
the market in the same strength.
False
Different products of the same API are present in
the market in different strength.
Type of dosages and their effects
Theraputic dosage - Safe
Toxic dosage - side effects
Lethal dosage - can kill ×_×
• Cyclophosphamide (Cytoxan) 50 mg tablets are
used in the treatment of neoplasms (abnormal
growths or tumors) and have a recommended dose
of 5 mg/kg of body weight to be given in a single
dose daily.
• How many tablets should be dispensed to a 110-lb
patient as a ten-day regimen?
50 tablets
If Tetanus antitoxin is an intramuscular or subcutaneous injection, given in a single dose ranging between 1500-10,000 units, as prophylaxis against tetanus. How many millilitres of tetanus antitoxin (1500 units/mL) must be injected to give the patient 2500 units.
1.67mL
Which is better: formulas that deal with patients’ sizes or with patients’ age?
Patients’ size
We can calculate the child dose from the adult dose using the following formulas:
Nomogram method
Fried’s rule
Young’s rule
Clark’s rule
What is the best formula when calculating the child dose?
Nomogram method
The adult (68-70kg) body surface area in meters square
1.73m²
Nomogram formula
Child dose = (Child surface area in m² × Adult dose) / 1.73m²
The adult dose of erythromycin is 250 mg to be given four times daily. Calculate the dose for a child who weighs 22 lbs and is 30 inches tall. Nomogram reading for the child is 0.46 m².
66.5mg
Fried’s rule
Child dose = (Child age in months / 150 month) × Adult dose
