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Week 8: Medicines used for GI diseases > Tut Q's > Flashcards

Tut Q's Flashcards

1
Q

Which of the following medicines is NOT an antiemetic that inhibits the chemoreceptor trigger zone (CTZ) by acting on dopamine D2 receptor as an antagonist?

A

Maropitant

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2
Q

Main mechanisms for stomach acid production include all of the following, EXCEPT:

A

Increased PGE2 secretion

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3
Q

Which of the following medicines is an emetic that should not be used in cats?

A

Apomorphine

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4
Q

Of the following alternatives, which one best describes the pharmacological actions of bismuth salicylate?

A

Reduces gastrointestinal tract’s secretory activity and provides anti-inflammatory effect.

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5
Q

Which of the following is an effective antiemetic medicines for use in cats?

A

Maropitant

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6
Q

A medicine used for managing animals with gastrointestinal conditions which stimulates the chemoreceptor trigger zone (CTZ) as an alpha 2 agonist is:

A

Xylazine.

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7
Q

An osmotic laxative medicine which is often used for the management of horse sand colic is:

A

Magnesium Sulphate

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8
Q

What class of gastrointestinal medicines below does metoclopramide fit best into?

A

Weak prokinetic medicines

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9
Q

Which of the following is most correct regarding the predominant mechanism of action of ondansetron?

A

Serotonin 5HT-3 receptor antagonist.

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10
Q

Which of the following statements about the mechanism of action of docusate sodium is most correct?

A

It has surfactant action on stools, allowing fluid and fat to penetrate the faecal mass.

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11
Q

One approach for the treatment of gastritis and gastric ulcers in small animals is inhibition of gastric acid secretion. Which of the following is NOT correct about antiulcer medicines that work by this approach?

A

Acting as a prostaglandin E2 antagonist to reduce acid secretion from the parietal cells.

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12
Q

Which of the following is most correct regarding the predominant mechanism of action of aminopentamide?

A

Muscarinic M1 receptor antagonist.

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13
Q

A medicine used for managing animals with gastrointestinal conditions which stimulates the chemoreceptor trigger zone (CTZ) as a dopamine D2 agonist is

A

Apomorphine.

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14
Q

Which of the following statements best describes the mechanism of action of prokinetic medicines cisapride and tegaserod?

A

They are serotonin 5HT4 receptor agonist

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15
Q

Of the following alternatives, which one best describes the clinical uses of diazepam and cyproheptadine in animals?

A

As appetite stimulants in cats.

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16
Q

Which of the following is NOT correct regarding the mechanism of actions of phenothiazine antiemetic medicines?

A

They are opioid mu receptors antagonist.

17
Q

An antiemetic medicine which acts predominantly on peripheral dopamine D2 receptors in the gastrointestinal tracts as an antagonist is:

A

Domperidone

18
Q

Which of the following is most correct regarding the predominant mechanism of action of maropitant?

A

Neurokinin NK1 receptor antagonist.

19
Q

Which of the following medications cannot be used to manage animals with diarrhoea?

A

Metoclopramide

20
Q

Which of the following is the dominant receptor type for antiemetic and emetic medications in the higher centre?

A

Acetylcholine Receptors

21
Q

Misoprostol prevents gastric ulceration by which mechanism?

A

PGE analog

22
Q

What is the action of apomorphine?

A

Agonist of the dopamine D2 receptor at the chemoreceptor trigger zone (CTZ) to cause vomiting.

23
Q

What is NOT correct about metoclopramide?

A

It can only be given IV

24
Q

Which medicine works at the CTZ?

A

Metoclopramide.

25
Q

Which of the following is NOT correct regarding kaolin?

A

It works by reducing gastrointestinal excessive secretion.

26
Q

Which of the following is NOT a reason why anti-emetics would be used in animals?

A

In cases of toxin ingestion.

27
Q

What is the function of anti-emetic medicines?

A

To stop vomiting

28
Q

Which of the centres does not control vomiting?

A

Paraventricular nuclei.

29
Q

Which of the following is the dominant receptor type for antiemetic and emetic medications in the peripheral regions/areas?

A

Muscarinic receptors.

30
Q

Which of these medicines is an effective emetic for use in cats?

A

Xylazine

Week 8: Medicines used for GI diseases (7 decks)

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