anti emetics

Question 1

why use anti emetics

Answer 1

• prevent animals from dehydration
• to reduce pain
• prevent loss of electrolytes
• given for conditions such as parvovirus, pancreatitis, eating toxins

Question 2

examples of the drug

Answer 2

Maropitant

• targets NK1 therefore useful for both peripheral areas in GI system and vomiting center
• long DOA, only given once daily
• use in dogs and cats

Ondansetron, dolasetron & granisetron

• target serotonin receptors
• used when using cytotoxic drugs & chemotherapy

Metoclopramide

• not used often, but effective - short DOA (given every 8 hrs)
• subjected to hepatic first-pass metabolism
• IV, IM or CRI

back up options if these 3 aren’t suitable for the animal

• prochlorperazine
• chlorpromazine
• acepromazine