Tut Q's Flashcards
Which of the following statements is NOT correct regarding the mechanisms of resistance of microbes to the effects of β-lactam antimicrobials?
Gram –ves can develop cell wall that is inherently more permeable to β-lactam antimicrobials.
Regarding hypersensitivity to β-lactams, which of the following is most correct?
If animals are allergic to penicillins, they have a good chance of being allergic to amoxicillin.
About the pharmacokinetics of β-lactam antimicrobial medicines, which of the following statements is NOT correct?
They have good distribution into eye, prostate and non-inflamed CNS.
Of the following classes/subclasses of antimicrobial medicines, which one is most likely to cause chondrotoxicity such as cartilage deformity and should not be used in young, growing animals?
Fluroquinolones
Which of the following statements about the use of β-lactamase inhibitors is NOT correct? \
Clavulanic acid is often combined with cephalexin.
Which of the following alternatives most correctly lists antimicrobial medicines that are CYP inhibitors?
Enrofloxacin, chloramphenicol.
Of the following classes/subclasses of antimicrobial medicines which one is most likely to cause blindness in cats?
Fluroquinolones
Regarding pharmacokinetics and clinical use of cefovecin, which of the following statements is NOT correct?
It has very low plasma protein binding.
Which of the following alternatives best describes antimicrobial medicines that are 3rdgeneration cephalosporin?
Ceftiofur, cefovecin.
Which of the following antimicrobials would be the best choice for the treatment of Staph pyoderma in dogs?
Cephalexin
Of the following medicines, which one is a 1stgeneration cephalosporin antimicrobial that is used for mastitis?
cephalonium
Regarding clinical uses of Clavulox (amoxicillin + clavulanic acid), which of the following statements is NOT correct?
The combined formulation is well suited for the treatment of mastitis and abscess.
Regarding pharmacokinetics and clinical use of ceftiofur, which of the following statements is NOT correct?
it’s a 1st generated cephalosporin
About hypersensitivity reactions to β-lactam antimicrobials, which of the following is NOT correct?
β-lactam antimicrobials should never be used in young animals and lactating animals.
Aminoglycoside antimicrobials have relatively higher toxicity than other antimicrobial classes. Which of the following statements about their toxicity is most correct?
Toxicity is due to drug accumulation at high concentration in the affected tissues.
