turnover and repair quiz Flashcards
turnover of epithelium occurs as the newly formed deepest cells migrate_______ from their formation near the _______
superficially
basement membrane
the time taken for a cell to divide and pass through the entire thickness of tissue
turnover time
in order to migrate, the cells release and then regain their _______ from their intercellular junctions in the more superficial location
desmosomal connections
the turnover time is higher for epithelium or connective tissue?
epithelium
the higher turnover time is a result of the _____ level of mitosis in those deepest diving cells near the basement membrane
higher
the older, superficial epithelial cells are being shed or lost______ as deeper germinal cells are dividing into more cells
at the same rate
what epithelium has a higher turnover time than the epidermis of skin?
oral mucosa
the differences of turnover time are especially noted during repair or healing of the tissue after ____
injury
the epithelium that lines the cheek (buccal mucosa) has higher turnover time than the ep of the
skin(27 days)
buccal(14 days)
turnover time for hard palate
24 days
turnover time for floor of mouth
20 days
turnover time for buccal and labial mucosa
14 days
turnover time for attached gingiva
10 days
turnover time for taste buds
10 days
turnover time for junctional epithelium(attached to tooth)
4-6 days
immediately after an injury to either the skin or oral mucosa, a ___ from blood products forms in the area, and the inflammatory response is triggered by the bloods white blood cells as they migrate into the tissue
clot
the epithelial cells at the ____ of the injury will lose their desmosomal intercellular junctions and ___ to form a new epithelial surface layer beneath the clot
periphery
desmosomal
turnover of ct proper in skin or oral mucosa occurs as a result of the production of____ and _____ by _____
fibers
intercellular substance
fibroblasts
when injured, the ct proper in the skin or oral mucosa goes through stages of repair that are ____ to the events in the more superficial epithelium
related
after a clot forms and a inflammatory response is triggered with WBC, ____ migrate to produce an immature ct deep to the clot and newly forming epithelial surface
fibroblasts
the immature connective tissue is considered_____ and has few fibers and an increased number of blood vessels
granulation tissue
appears as a redder, soft tissue that bleeds easily
granulation tissue
may become abundant and can interfere with the repair process. surgical removal of excess granulation tissue may be necessary to allow for optimum repair. sometimes occurs after the extraction of teeth or with periodontal disease
granulation tissue
later, during the repair process, this temporary granulation tissue is replaced by paler and firmer ______ in the area
scar tissue
contains an increased number of fibers and fewer blood vessels
scar tissue
what shows more scar tissue both clinically and microscopically after repair than does the oral mucosa
skin
unlike skin and lips, the oral mucosa is ____ from changes due to ultraviolet radiation
protected
it is sometimes_____ to distinguish oral mucosa changes caused by aging from changes caused by chronic disease
difficult
in some regions of oral mucosa, there is a slight ____ of the epithelium with a concomitant flattening of the epithelial-connective tissue interface
thinning
aging of oral mucosa:there is a reduction of ___ on the attached gingiva
stippling
aging of oral mucosa: an increase in _____ in the labial and buccal mucosa
fordyce’s spots
aging of oral mucosa: enlargement of ____ veins to form lingual varicosities on the ventral surface of tongue
lingual
aging of oral mucosa: the _____ decrease in quantity, appear smaller, and are less active in older oral mucosa
fibroblasts
aging of oral mucosa: the ____ has a slower collagen turnover time
entire lamina propria
aging of oral mucosa: the ability of the oral mucosa to repair itself is____ and the length of the repair time is _____ just as turnover time
reduced
increased
the number of lingual papillae, especially the ___ lingual papillae, and associated taste buds is also reduced and may be related to changes in taste perception
foliate
changes in the salivary glands that result in less production of saliva
hyposalivation
less production of saliva, which makes the oral mucosa drier and less protective
xerostomia
less defined division between the ___ and dense layers of lamina propria with age
papillary
in older oral mucosa, collagen fibers appear ____ and arranged into dense bundles resembling those found in tendons or ligaments
thickened
elastic fibers in older oral mucosa, if present in lamina propria, appear ____ even though more of them are present; loss of resiliency found in aged oral mucosa
changed
