Tumours of the Mediastinum Flashcards
Localisation of neurogenic tumours
Posterior Mediastinum
Neuroblastoma in children are usually
Malignant
Ganglioneuroma in adults are usually
Benign
Localization of malignant lymphomas
Anterior mediastinum
Common type of malignant lymphomas
Nodular Sclerosing Hodgkin Lymphoma
Epidemiology of malignant lymphomas
Female > Male
Localisation of pericardial cyst
Middle Mediastinum
Localisation of Teratomas
Anterior Mediastinum
Grading of teratomas
Benign Cystic Teratomas: Commonly
contain a mixture of squamous and glandular somatic
epithelium, as well as cartilage or bone
Minority -> Malignant Teratomas: Primitive neuroepithelial tissue, represented by embryonic tubules
Localisation of Thymomas
Anterior Mediastinum
Grading of thymomas
Benign 70%
Malignant 30%
Clinical Features of thymomas
Systemic symptoms of Myasthenia Gravis (MG)
Hypoglammaglobulinaemia
Pure RBC aplasia
High Incidence of autoimmune diseases (e.g. Graves)
Thymoma types
Lymphocyte predominant
Epithelial
Mixed lymphoepithelial
Spindle cell