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Pathology Basics - step > Tumour Markers and Oncogenic Moos > Flashcards

Tumour Markers and Oncogenic Moos Flashcards

1
Q

alkaline phosphatase

A

metastases to bone or liver
paget disease of bone
seminoma (placental ALP)

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2
Q

alpha fetoprotein

A

hepatocellular carcinoma
hepatoblastoma
yolk sac/endodermal sinus tumour
mixed germ cell tumour

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3
Q

beta-HCG

A

hydatidiform moles
choriocarcinomas/gestational trophoblastic disease
testicular cancer
mixed germ cell tumours

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4
Q

CA 15-3/CA 27-29

A

breast cancer

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5
Q

CA 19-9

A

pancreatic adenocarcinoma

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6
Q

CA 125

A

ovarian cancer

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7
Q

calcitonine

A

medullary thyroid carcinoma

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8
Q

CEA

A 
carcinoembryonic antigen
VERY NON SPECIFIC
but 70% of colon colorectal and pancreatic cancers
gastric
breast
medullary thryodi carcinnomas too
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9
Q

chromogranin

A

neuroendocrine tumours/carcinoids

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10
Q

PSA

A

prostate cancer
BPH
prostatitis

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11
Q

EBV virus

A

burkitt lymphoma
Hodgkin lymphoma
nasopharyngeal carcinoma
primary CNS lymphoma in immunocompromised patients

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12
Q

HBV

HCV

A

hepatocellular carcinoma

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13
Q

HHV-8

A

Kaposi sarcoma

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14
Q

HPV

A

cervical carcinoma
penile/anal carcinoma
head and neck cancer

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15
Q

H pylori

A

gastric adenocarcinoma

MALT lymphoma

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16
Q

HTLV-1

A

adult T cell leukemia/lymphoma

17
Q

Liver fluke/clonorchis sinensis

A

cholangiocarcinoma

18
Q

schistosoma haematobium

A

squamous cell bladder cancer

Pathology Basics - step (6 decks)

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