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Pharma 300 > Tumortherapeutika > Flashcards

Tumortherapeutika Flashcards

1
Q

Cyclophosphamid

A

Hauptvertreter der Alkylantien, prodrug, hämorrhag. Cystitis

(MESNA) Tumortherapeutika

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2
Q

Cisplatin, Oxaliplatin

A

direkte Interkalation DNA, Cisplatin stark emetisch Tumortherapeutika

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3
Q

Methotrexat

A

in hoher Dosis als Antimetabolit zytostatisch, Antidot

Folinsäure Tumortherapeutika

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4
Q

Paclitaxel

A

Stabilisation von Mikrotubuli Tumortherapeutika

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5
Q

Vincristin

A

Hemmung der Polymerisation von Tubulin zu Mikrotubuli Tumortherapeutika

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6
Q

Etoposid, Irinotecan

A

Topoisomerasehemmer Tumortherapeutika

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7
Q

Doxorubicin

A

zytostatisches Antibiotikum, Herztoxizität Tumortherapeutika

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8
Q

5-Fluorouracil

A

falsche Base einbau & folinsäure/methotrexat nur 1/4 der dosis Tumortherapeutika

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9
Q

6-Mercaptopurin

A

falscher basen einbau cave Allopurinol (1/4 Dosis!)+TPMT-Polymorphismus Tumortherapeutika

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10
Q

Tamoxifen

A

Selektiver Östrogen Rezeptormodulator („Anti-Östrogen“)
zur adjuvanten Therapie bei HR+-Mamma-Ca,
prämenopausal Tumortherapeutika

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11
Q

Anastrozol, Letrozol

A

Aromatasehemmer bei HR+-Mamma-Ca postmenopausal Tumortherapeutika

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12
Q

Leuprorelin

A

Gonadorelinanalog bei fortgeschr. Prostata-CaTumortherapeutika

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13
Q

Bicalutamid

A

Anti-Androgen bei fortgeschr. Prostata-Ca Tumortherapeutika

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14
Q

Trastuzumab (Herceptin

A

Antikörper gegen HER2 (Mamma-Ca) Tumortherapeutika

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15
Q

Imatinib (Glivec®

A

Tyrosinkinasehemmer bei CML (Bcr-Abl) Tumortherapeutika

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Pharma 300 (65 decks)

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