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Pharma 300 > Gerinnungshemmer > Flashcards

Gerinnungshemmer Flashcards

1
Q

Heparin unfraktioniert

A

älterer Standard, akutes Koronarsyndrom, Überbrückung,

Schwangerschaft

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2
Q

Heparin niedermolekular

(z.B. Enoxaparin

A

länger wirksam, keine PTT-Steuerung, Kumulation bei

Niereninsuffizienz

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3
Q

Hirudin

A

Direkter Thrombininhibitor, NUR bei HIT II

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4
Q

Fondaparinux

A

selekt. Antithrombin-abhängige Faktor Xa-Hemmung, nur

s. c.

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5
Q

Phenprocoumon

A

Standard (wird zunehmend ersetzt), orale Antikoagulation

bei VHF, Thrombose, Lungenembolie aber CYP, und überbrückung nötig und teratogen

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6
Q

Dabigatran

A

direkte reversible Thrombin-Hemmung, oral

Antidot: Idarucizumab cave Kumulation nieren

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7
Q

Rivaroxaban

A

direkte reversible Faktor Xa-Hemmung, oral, breitestes
Indikationsspektrum Antidot: Andexanet alfa,
CYP!

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8
Q

Apixaban

A

direkte reversible Faktor Xa-Hemmung, oral CYP!

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9
Q

Edoxaban

A

direkte reversible Faktor Xa-Hemmung, oral, jüngster

Vertreter

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Pharma 300 (65 decks)

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