Tumors with characteristic chromosomal defects Flashcards

1
Q

Chronic Myelogenous Leukemia

A

Translocation between chromosome 22 and chromosome 9 (Philadelphia chromosome)

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2
Q

Burkitt’s Lymphoma

A

Translocation from 8 to 14

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3
Q

Retinoblastoma

A

Deletion of chromosome 13

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4
Q

Wilm’s Tumor

A

Deletion of chromosome 11

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5
Q

Neuroblastoma

A

Gene amplification (N-myc)

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