Breast I

Question 1

Inflamatory disorder associated with breast feeding, usually 1 month post-partum

Answer 1

Acute mastitis

Question 2

Inflammatory disorder associated with prosthesis and piercings

Answer 2

Granulomatous mastitis

Question 3

Inflammatory disorder associated with autoimmune diseases such as Type 1 Diabetes

Answer 3

Lymphocytic mastitis

Question 4

Painless breast mass

Answer 4

Usually cancer

Question 5

Patient with a prior history of trauma or surgery with a painless breast mass

Answer 5

Fat necrosis

Question 6

Woman of reproductive years (25-45 y.o.) who has a history of drinking way to much caffeine and on exam has “lumpy, bumpy” breasts.

Answer 6

Fibrocystic Change

Question 7

Blue-domed cysts grossly

Answer 7

Fibrocystic Change

Question 8

Histo: Apocrine cysts, adenosis (gland proliferation), and flecks of calcification

Answer 8

Fibrocystic Change

Question 9

30 y.o. with a breast lump

Histo: Prominent myoepithelial cells and a swirling pattern

Answer 9

Sclerosing adenosis

Question 10

50 y.o with breast lump

Histo: Stellate or flower-head pattern

Answer 10

Radial scar

Question 11

Histo: Ducts that are greater than 2 cell layers thick

Answer 11

Epithelial hyperplasia

Typical- 1-2x the risk of cancer

Atypical: 4-5x the risk of cancer

Question 12

45 year old woman presents with bloody nipple discharge, what would you see histologically?

Answer 12

Papillary fibrovascular core projecting into a dilated duct

Question 13

1 benign neoplasm of the breast

Answer 13

Fibroadenoma

Question 14

A tumor that enlarges and regresses with the menstrual cycle

Answer 14

Fibroadenoma

Question 15

Grossly, this tumor is sharply circumscribed and freely moveable

Answer 15

Fibroadenoma

Question 16

Patient is over 50 years old with a tumor that looks a lot like a Fibroadenoma

Answer 16

Phyllodes tumor

20% of these are malignant

Question 17

BRCA 1 and BRCA 2 impart a lifetime risk of breast cancer of…

Answer 17

30-80%

Question 18

17q

Answer 18

BRCA1

Question 19

13q

Answer 19

BRCA2

Question 20

More common breast cancer mutation

Answer 20

BRCA 1

Question 21

Younger (40-50)

Answer 21

BRCA 1

Question 22

Less common breast cancer mutation

Answer 22

BRCA 2

Question 23

Older (50 yrs)

Answer 23

BRCA 2

Question 24

More ovarian cancer

Answer 24

BRCA 1

Question 25

Melanoma and gastric carcinoma

Answer 25

BRCA 2

Question 26

Ashkenazi Jewish

Answer 26

BRCA 1

Question 27

Medullary and mucinous subtypes of breast cancer

Answer 27

BRCA 1

Question 28

Where is the majority of breast cancer located?

Answer 28

Upper outer quadrant, more often on the left than right breast