Malnutrition Flashcards
Caused by a decrease in calorie intake
Marasmus
Caused by a decrease in calorie intake
Marasmus
Alert kid with muscle wasting, loss of sub-Q fat, and normal serum albumin levels
Marasmus
Caused by a decrease in protein intake
Kwashiorkor
Extremely apathetic child who has a protuberant abdomen, sparing of the subcutaneous fat, edema, and a fatty liver
Kwashiorkor
Malnutrition complicating advanced disease. Will see extreme weight loss, fatigue, muscle wasting, and anemia
Cachexia
Self-imposed starvation
Anorexia Nervosa
This can cause endocrine abnormalities such as amenorrhea and changes of hypothyroidism. Decreased bone density, anemia, and hypokalemia
Alert kid with muscle wasting, loss of sub-Q fat, and normal serum albumin levels
Marasmus
Caused by a decrease in protein intake
Kwashiorkor
Extremely apathetic child who has a protuberant abdomen, sparing of the subcutaneous fat, edema, and a fatty liver
Kwashiorkor
Malnutrition complicating advanced disease. Will see extreme weight loss, fatigue, muscle wasting, and anemia
Cachexia
What BMI is considered to be malnutrition?
Self-imposed starvation
Anorexia Nervosa
This can cause endocrine abnormalities such as amenorrhea and changes of hypothyroidism. Decreased bone density, anemia, and hypokalemia
Binge eating followed by compensatory behaviors
Bulimia.
The vomiting will often put these patients into a Metabolic Alkalosis.
Found in leafy green vegetables
Vitamin A
A patient comes in with a headache, vomiting, stupor, and papilledema. These symptoms suggest what?
Acute Vitaminosis A
Excess of Vitamin A
Deficiency in this vitamin causes dry eyes (exerophthalmia)
Vitamin A
Deficiency in this vitamin causes squamous metaplasia of epithelium
Vitamin A
Deficiency in this vitamin causes immune deficiency
Vitamin A
When you look in the eye and you see white patchy stuff in it (Bitot’s spots) you suspect a deficiency in this vitamin
Vitamin A
A derivative of this vitamin is one of the main components of Acutane (isotretinoin)
Vitamin A
Remember that Acutane cannot be given to pregnant women, or women who may become pregnant.
A patient comes in with a headache, vomiting, stupor, and papilledema. These symptoms suggest what?
Acute Vitaminosis A
Excess of Vitamin A
Rickets is a deficiency in…
Vitamin D in children
What is the active form of vitamin K?
K1
K2 is the inactive form. Vitamin K is also needed for the gamma-carboxylation of glutamate residues. Vitamin K is not in breast milk, so it must be given as an injection at birth.
What can an excess of Vitamin D lead to?
Hypercalcemia, renal stones, and ectopic calcification
This vitamin is an antioxidant that protects erythrocytes from free radical damage
Vitamin E
Wet Beri-Beri
Vitamin B1 (Thiamine). Dilated cardiomyopathy and edema
This vitamin is a co-factor for clotting factors II, VII, IX, and X and proteins C and S
Vitamin K
This vitamin is antagonized by Warfarin
Vitamin K
What is the active form of vitamin K?
K1
K2 is the inactive form. Vitamin K is also needed for the gamma-carboxylation of glutamate residues.
Chronic alcoholic presents with opthalmoplegia, confusion, and ataxia. What vitamin is he deficient in?
Vitamin B1 (Thiamine). This is Wernicke-Korsakoff Syndrome.
Dry Beri-Beri
Vitamin B1 (Thiamine). Presents as polyneuritis with symmetrical muscle wasting.
Wet Beri-Beri
Vitamin B1 (Thiamine). Dilated cardiomyopathy and edema
FAD and FMN are derived from…
Vitamin B2 (Riboflavin)
Deficiency in Vitamin B2 can lead to…
Cheilosis (scaling at the corners of the mouth) and Corneal vascularization
Patient presents with dementia, dermatitis (glove distribution of a red, scaly appearance on sun exposed areas), and diarrhea
Vitamin B3 (niacin). This disease is known as Pellagra.
Corn only diet will cause this deficiency
Pellagra
What is vitamin B6 (Pyridoxine) used for?
Cofactor in protein synthesis
This vitamin deficiency can be secondary to drugs, alcohols, or pregnancy
Vitamin B6
This vitamin is absorbed in the terminal ileum attached to intrinsic factor
Vitamin B12
Vitamin B12 is also a cofactor in odd chain fatty acid metabolism and DNA synthesis
Lack of Vitamin B12 (cobalamin) causes what?
Pernicious anemia and degeneration of the posterolateral spinal cord tracts (Subaute Combined Degeneration)
This vitamin is required for normal folate metabolism and DNA synthesis
Vitamin B12 (Cobalamin)
A deficiency in which vitamin is seen in vegans, and those infected with the fish tapeworm Diphyllobothrium latum?
Vitamin B12 (Cobalamin) Diphyllobothrium latum eats 80% of the body's vitamin B12
This vitamin is converted to tetrahydrofolate (THF), a coenzyme for 1-carbon transfers. It is important for synthesis of nitrogenous bases of DNA and RNA.
Vitamin B9 (folic acid)
A deficiency in this vitamin causes Megaloblastic anemia and Neural Tube Defects
Vitamin B9 (folic acid)
Folate antagonists include:
Chemotherapeutic agents (phenytoin, sulfonamides, methotrexate) Oral contraceptives Anticonvulsants Ethanol Cigarette Smoking
Patient presents with petechial hemorrhage of the skin, subperiosteal hematomas, bleeding into the joint space, swollen bleeding gums and tooth loss. What vitamin is deficient?
Vitamin C (Ascorbic acid) The disease described is Scurvy.
Functions of Vitamin C
Antioxidant.
Facilitates iron absorption by reducing it to Fe+2 state.
Necessary for hydroxylation of proline and lysine in collage synthesis.
Lab findings of peripheral blood smear: Large red cells with an MCV > 100 and hypersegmented neutrophils
Megaloblastic anemia due to a folate deficiency (Vitamin B9)
A deficiency in iron will lead to…
Hypochromic microcytic anemia
A deficiency in zinc is found in…
Children who eat clay (clay binds zinc)
A deficiency in zinc causes:
Acrodermatitis enteropathica (rash around the eyes, mouth, nose, and anus) Growth retardation, impaired wound healing, anorexia, impaired night vision, depressed mental function, and congenital malformations
This trace element is a component of glutathione peroxidase and an antioxidant with vitamin E
Selenium
A deficiency in selenium causes…
Myopathy..."White Muscle Disease" Keshan Disease (congestive cardiomyopathy)
A deficiency of iodine would lead to…
Goiter, Hypothyroidism, and Cretinism
A deficiency in this trace element would result in muscle weakness, neurologic defects, and abnormal collagen cross-linking
Copper
Metabolic Syndrome
I) Increased adiposity
II) Glucose intolerance
III) Hypertension
IV) Dyslipidemia
Normal BMI
18.5-25
Malnutrition BMI
Overweight BMI
25-30
Obese BMI
> 30