Tumors of the liver and biliary tree Flashcards

1
Q

hepatocellular carcinoma

  • sex predominance?
  • major cause in the US vs OUS?
  • other etiology?
A
  • male or >40
  • alcohol vs HepC
  • hemochromatosis, Wilsons, T2 Diabetes, HBV…
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2
Q

Types of HCC?

A

solitary
diffuse
fibrolamella
adenoma (benign)

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3
Q

Primary hepatic tumor types:

A
  • hepatocellular
  • cholangiocarcinoma
  • hepatoblastoma
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4
Q

primary hepatic tumors- clinical manifestations/symptoms:

A
  • WL
  • weakness
  • abdominal pain/mass
  • portan HTN
  • jaundice
  • ascites
  • bleeding
  • fever
  • hepatomegally***
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5
Q

primary hepatic tumors - diagnostics:

A
  • liver function tests
  • alpha feto proteins
  • ultra sounds
  • MRI
  • computer tomography-hypervasculairy with washout
  • MRI
  • nuclide scanning
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6
Q

Primary hepatic tumors treatment options?

A
  • surgical removal
  • liver transplant
  • cryoablation
  • radiation therapy
  • etc
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7
Q

Hepatoma expectancy?
-resection
transplant?

A
  • 27-32% ish

- 40-75%

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8
Q

Hepatoblastoma survival less than 2yo?

A

90+%

poor if in adult

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9
Q

Just read notepool stuff…

A

Just read notepool stuf

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10
Q

risk factors for cholangiocarcinoma?

A
  • PSC
  • liver fluke
  • congenital liver malformation
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11
Q

most common locatio n for cholangiocarcinoma?

A

junction of right and left hepatic ducts

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12
Q

choangiocarcinomas are what kind of cancer?

A

adenocarcinoma

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13
Q

presentation of cholangiocarcinoma?

A
  • painless jaundice

- itching

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14
Q

What is the name/test for a palpable gallbladder?

A

-courvoisiers sign

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15
Q

Cholangiocarcinoma lab/markers?

A
  • carcinoembryonic antigen

- CA 19-9

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