Tumors of the liver and biliary tree Flashcards
hepatocellular carcinoma
- sex predominance?
- major cause in the US vs OUS?
- other etiology?
- male or >40
- alcohol vs HepC
- hemochromatosis, Wilsons, T2 Diabetes, HBV…
Types of HCC?
solitary
diffuse
fibrolamella
adenoma (benign)
Primary hepatic tumor types:
- hepatocellular
- cholangiocarcinoma
- hepatoblastoma
primary hepatic tumors- clinical manifestations/symptoms:
- WL
- weakness
- abdominal pain/mass
- portan HTN
- jaundice
- ascites
- bleeding
- fever
- hepatomegally***
primary hepatic tumors - diagnostics:
- liver function tests
- alpha feto proteins
- ultra sounds
- MRI
- computer tomography-hypervasculairy with washout
- MRI
- nuclide scanning
Primary hepatic tumors treatment options?
- surgical removal
- liver transplant
- cryoablation
- radiation therapy
- etc
Hepatoma expectancy?
-resection
transplant?
- 27-32% ish
- 40-75%
Hepatoblastoma survival less than 2yo?
90+%
poor if in adult
Just read notepool stuff…
Just read notepool stuf
risk factors for cholangiocarcinoma?
- PSC
- liver fluke
- congenital liver malformation
most common locatio n for cholangiocarcinoma?
junction of right and left hepatic ducts
choangiocarcinomas are what kind of cancer?
adenocarcinoma
presentation of cholangiocarcinoma?
- painless jaundice
- itching
What is the name/test for a palpable gallbladder?
-courvoisiers sign
Cholangiocarcinoma lab/markers?
- carcinoembryonic antigen
- CA 19-9