Tumor suppressor genes and their cancers Flashcards

1
Q

APC

A

carcinoma of stomach, colon, pancreas; melanoma

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2
Q

NF1

A

neuroblastoma, juvenile myeloid leukemia

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3
Q

NF2

A

schwannoma, meningioma

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4
Q

PTCH

A

basal cell carcinoma, medulloblastoma

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5
Q

VHL

A

renal cell carcinoma

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6
Q

CDH1

A

gastric carcinoma, lobular breast carcinoma

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7
Q

BRCA1, BRCA2

A

Rare breast cancer

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8
Q

MSH2, MLH1, MSH6

A

colonic and endometrial carcinoma

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9
Q

WT1

A

wilms tumor, certain leukemia

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