Proto-oncogenes and their tumors Flashcards

1
Q

ERBB1

A

Adenocarcinoma of the lung

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2
Q

ERBB2

A

Breast Carcinoma

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3
Q

ALK

A

adenocarcinoma of lung, certain lymphomas, neuroblastoma

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4
Q

KRAS

A

Colon, lung, pancreatic tumors

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5
Q

BRAF

A

melanomas, leukemias, colon carcinoma, others

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6
Q

MYC, NMYC

A

burkitt lymphoma, neuroblastoma

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7
Q

SHH (and Wnt)

A

basal cell carcinoma

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8
Q

HRAS

A

Bladder and kidney

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9
Q

NRAS

A

Melanomas, hematologic malignancies

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10
Q

GNAQ

A

Uveal melanoma

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11
Q

GNAS

A

Pituitary adenoma, other endocrine tumors

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