tumor suppressor genes Flashcards by Sam Lucrezia

Q

APC

A

colorectal cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

BRCA1/2

A

DNA repair protein - breast and ovarian cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

DCC

A

colon cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

DPC4/ SMAD4

A

pancreatic cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

MEN1

A

Pituitary adenoma, pancreatic adenoma, parathyroid adenoma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

NF1

A

neurofibromas
cafe au lait spots
lisch nodules

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

NF2

A

schwannomas

gliomas, meningiomas

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

P16

A

Cyclin dependent kinase inhibitor 2A

melanoma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

P53

A

blocks G1 –> S phase

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PTEN

A

breast, prostate, endometrial cancer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

RB

A

inhibits E2F, blocks G1 –> s

retinoblastoma, Osteosarcoma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

VHL

A

renal cell carcinoma

inhibits hypoxia inducible factor 1a

How well did you know this?

1

Not at all

2

3

4

5

Perfectly