TUMOR ODONTOGÉNICO QUERATOQUISTICO Flashcards

1
Q

¿Que son los tumores odontogenicos queratoquisticos TOQ?

A

Neoplasia benigna intraosea agresivo e infiltrativo compromete cortical hueso

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2
Q

Cual es su clinica

A

Asintomaticos
Movilidad dentaria
Reabsorcion osea

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3
Q

Amelobalstoma que es?

A

Neoplasia invasiva ,patron folicular o plexiforme en estroma fibroso,asintomatico

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4
Q

Marcadores de actividad neoplasica malignas

A

p53

ki 67

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5
Q

rol p53

A

Impide la division celular con material genetico dañado
Induce apoptosis
Inhibe replicacion transcripcional

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6
Q

concentracion p53 en celula normal

A

bajo

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7
Q

concentracion p53 en celula cancerosa

A

alto

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8
Q

vida media p53

A

15 a 20 minutos

En condicion normal no es detectada por inmunohistoquimica

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9
Q

Ki 67

A

detecta antigeno nuclear se expresa en celulas que entran ciclo celular G1 ,S,G2,mitosis por eso es util evaluar proliferacion tumores
TNM avanzados
Metastasis

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