Tumor Necrosis Factor (TNF) Flashcards
Tumor cytotoxicity; cachexia
Tumor Necrosis Factor
Antiviral (IFN-like) and antiparasitic activity
Tumor Necrosis Factor
Activation of phagocytic cells
Tumor Necrosis Factor
Induction of IFN-γ, IL-1, GM-CSF, and IL-6
Tumor Necrosis Factor
Endogenous pyrogen to induce fever; induction of APR
Tumor Necrosis Factor
Cachetin
Tumor Necrotic Factor (TNF)-α
Local inflammation, acute phase proteins
Tumor Necrotic Factor (TNF)-α
Lymphotoxin
Tumor Necrotic Factor (TNF)-β
Killing of target cells
Tumor Necrotic Factor (TNF)-β
Produced mainly by macrophages (promotes inflammation)
Tumor Necrosis Factor
Macrophages
NK cells
Tumor Necrotic Factor (TNF)-α
T cells (CD4 & CD8)
B cells
Tumor Necrotic Factor (TNF)-β