Tumor Necrosis Factor (TNF) Flashcards

1
Q

Tumor cytotoxicity; cachexia

A

Tumor Necrosis Factor

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2
Q

Antiviral (IFN-like) and antiparasitic activity

A

Tumor Necrosis Factor

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3
Q

Activation of phagocytic cells

A

Tumor Necrosis Factor

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4
Q

Induction of IFN-γ, IL-1, GM-CSF, and IL-6

A

Tumor Necrosis Factor

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5
Q

Endogenous pyrogen to induce fever; induction of APR

A

Tumor Necrosis Factor

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6
Q

Cachetin

A

Tumor Necrotic Factor (TNF)-α

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7
Q

Local inflammation, acute phase proteins

A

Tumor Necrotic Factor (TNF)-α

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8
Q

Lymphotoxin

A

Tumor Necrotic Factor (TNF)-β

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9
Q

Killing of target cells

A

Tumor Necrotic Factor (TNF)-β

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10
Q

Produced mainly by macrophages (promotes inflammation)

A

Tumor Necrosis Factor

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11
Q

Macrophages
NK cells

A

Tumor Necrotic Factor (TNF)-α

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12
Q

T cells (CD4 & CD8)
B cells

A

Tumor Necrotic Factor (TNF)-β

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