Surface Markers on T and B Cells Flashcards

1
Q

Involved in T cell activation

A

CD2

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2
Q

Associated with T cell antigen receptor; role
in T cell receptor transduction

A

CD3

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3
Q

Co-receptor for MHC II; receptor for HIV

A

CD4

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4
Q

Positive or negative modulation of T and B cell receptor signaling

A

CD5

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5
Q

Co-receptor for MHC I

A

CD8

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6
Q

Protease; a marker for pre-B common acute
lymphocytic antigen (CALLA)

A

CD10

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7
Q

Low-affinity Fc receptor mediates phagocytosis and ADCC

A

CD16

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8
Q

Part of B cell co-receptor, signal transduction molecule that regulates B
cell development and activation

A

CD19

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9
Q

Receptor for complement component C3d;
part of B cell co-receptor with CD19

A

CD21

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10
Q

Regulation of IgE synthesis; triggers the release of GM-CSF from monocytes

A

CD23

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11
Q

Receptor for IL-2

A

CD25

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12
Q

Adhesion molecule mediating homing to
peripheral lymphoid organs

A

CD44

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13
Q

Essential in T and B cell antigen-stimulated
activation

A

CD45R

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14
Q

Not known function
(NK cells, subsets of T cells)

A

CD56

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15
Q

Subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity

(NK cells, subsets of T cells)

A

CD94

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16
Q

Thymocytes, T cells, NK cells

A

CD2

17
Q

Thymocytes, T cells

A

CD3

18
Q

Helper T cells, monocytes, and macrophages

A

CD4

19
Q

Mature T cells, thymocytes, a subset of B cells (B1)

A

CD5

20
Q

Thymocyte subsets, cytotoxic T cells

A

CD8

21
Q

B and T cell precursors, bone marrow, stromal cells

A

CD10

22
Q

Macrophages, NK cells, neutrophils

A

CD16

23
Q

B cells, follicular dendritic cells

A

CD19

24
Q

B cells, follicular dendritic cells, a subset of immature thymocytes

A

CD21

25
Q

B cells, monocytes, follicular dendritic cells

A

CD23

26
Q

Activated T, B cells, monocytes

A

CD25

27
Q

Most leukocytes

A

CD44

28
Q

Different forms on all hematopoietic cells

A

CD45R