Tumor Markers Flashcards
0
Q
Normally made by fetus.
Hepatocellular carcinoma
Hepatoblastoma
Yolk sac tumor ( endodermal sinus )
Testicular cancer
Mixed germ cell tumor
*co-secreted with beta-hCG
A
Alfa-fetoprotein
1
Q
Alkaline phosphatase
A
Metastasis to bone, liver, paget disease of the bones, seminoma
2
Q
Beta-hCG
A
Hydratiform moles
Coriocarcinoma (gestational trophoblastic disease)
Testicular cancer
*commonly associated with pregnancy
3
Q
CA-15-3/CA-27-29
A
Breast cancer
4
Q
Pancreatic adenocarcinoma
A
Ca-19-9
5
Q
CA-125
A
Ovarian cancer
6
Q
Medullary thyroid carcinoma
A
Calcitonin
7
Q
CEA
A
CarcinoEmbryonicAntigen
- very non-specific
- produced by 70% of colonorectal and pancreatic cancer
- also prod. By gastric, breast, and medullary thyroid carcinoma
8
Q
Used to follow prostate adenocarcinoma
Can be elevated un BPH and prostatitis
A
PSA
9
Q
S-100
A
Neural crest origin
- melanomas
- neural tumors
- schwamomas
- langerham cell histiocytosis
10
Q
TAP
A
Tartrate-Resistant Acid Phosphatase (TRAP)
Hairy cell leukemia
B-cell neoplasm
