Oncogenes Flashcards
0
Q
Bcl-2
A
Tumor:
Follicular and undifferentiated lymphomas
Products:
Anti apoptotic molecule
1
Q
BCR-ABL
A
Tumor:
CML, ALL
Product:
Tyrosine kinase
2
Q
BRAF
A
Tumor:
Melanoma
Products:
Serine/threonine kinase
3
Q
C-kit
A
Tumor:
Gastrointestinal stromal tumor
Producs:
Cytokine receptor
4
Q
C-myc
A
Tumor:
Burkitt lymphoma
Products:
Transcription factor
5
Q
HER2/neu (c-erbB2)
A
Tumor:
Breast, ovarian, gastric carcinoma
Products:
Tyrosine kinase
6
Q
L-myc
A
Tumor:
Lung tumor
Products:
Transcription factor
7
Q
N-myc
A
Tumor:
Neuroblastoma
Products:
Transcription factor
8
Q
ras
A
Tumor:
Colon cancer, lung cancer, pancreatic cancer
Products:
GTPase
9
Q
ret
A
Tumor:
MEN 2a and 2b
Products:
Tyrosine kinase