Oncogenes Flashcards

0
Q

Bcl-2

A

Tumor:
Follicular and undifferentiated lymphomas
Products:
Anti apoptotic molecule

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1
Q

BCR-ABL

A

Tumor:
CML, ALL
Product:
Tyrosine kinase

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2
Q

BRAF

A

Tumor:
Melanoma
Products:
Serine/threonine kinase

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3
Q

C-kit

A

Tumor:
Gastrointestinal stromal tumor
Producs:
Cytokine receptor

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4
Q

C-myc

A

Tumor:
Burkitt lymphoma
Products:
Transcription factor

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5
Q

HER2/neu (c-erbB2)

A

Tumor:
Breast, ovarian, gastric carcinoma
Products:
Tyrosine kinase

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6
Q

L-myc

A

Tumor:
Lung tumor
Products:
Transcription factor

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7
Q

N-myc

A

Tumor:
Neuroblastoma
Products:
Transcription factor

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8
Q

ras

A

Tumor:
Colon cancer, lung cancer, pancreatic cancer
Products:
GTPase

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9
Q

ret

A

Tumor:
MEN 2a and 2b
Products:
Tyrosine kinase

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