Tumor

Question 1

Intralesional curettage and adjuvant treatment (e.g., phenol, hydrogen peroxide, argon beam, etc) is the treatment of choice for which benign bone tumor?

Answer 1

Giant cell tumor

Question 2

What is the associated translocation and fusion protein seen in Ewing’s sarcoma?

Answer 2

t (11:22), EWS-FL1.

Question 3

Which tumor is associated with the SYT-SSX1 fusion protein?

Answer 3

Synovial sarcoma

Question 4

What is the most common site for pathologic fracture secondary to metastasis to bone?

Answer 4

Proximal femur

Question 5

What is the most common site of metastasis for osteosarcoma?

Answer 5

lungs

Question 6

What is the 2nd most common site of metastasis for osteosarcoma?

Answer 6

bone

Question 7

What is the treatment for low-grade intramedullary osteosarcoma?

Answer 7

Wide resection alone

Question 8

While tumor has a “popcorn” stippled calcification and rings?

Answer 8

Enchondroma

Question 9

Which vascular tumor can arise following irradiation and poly-vinyl chloride exposure?

Answer 9

Angiosarcoma

Question 10

What is the name of the analogous histologic disease to PVNS when located away from the synovial lining of joints?

Answer 10

giant cell tumor of tendon sheath

Question 11

What is the chromosomal translocation for synovial sarcoma?

Answer 11

t(x;1)8

Question 12

What is the treatment of choice for symptomatic synovial chondromatosis?

Answer 12

arthroscopic removal of loose bodies

Question 13

Tumors that metastasize distal to the knees and elbows typically come from which primary tumors?

Answer 13

Renal or lung