Tubulo-Interstitial Disease

Question 1

Compare normal and disease interstitium

Answer 1

Normally inconspicuous

More visible in diseases where there is acute swelling or fibrosis

Question 2

What are the most important causes of tubulo-interstitial injury?

Answer 2

Ischaemic (or more rarely toxic) injury leading to ATN
Acute pyelonephritis (infection)
Acute or chronic tubulo-interstitial nephritis