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Urinary System > Tubular Reabsorotion And Secretion > Flashcards

Tubular Reabsorotion And Secretion Flashcards

1
Q

Makes largest contribution for Reabsorption

A

PCT

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2
Q

The transfer of material from blood and tubule cells into filtrate

A

Secretion

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3
Q

Two important out comes from secretion

A

Secretion of H ions help control blood pH

Secretion of other items help eliminate them from the body

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4
Q

The top of soda cans

A

Apical

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5
Q

Bottom and sides of soda cans

A

Basolateral

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6
Q

Apical membrane contacts what type of fluid

A

Tubular fluid

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7
Q

Basolateral membrane contacts what type of fluid

A

Interstitial

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8
Q

Two types of Reabsorption routes

A

Paracellular

Transcellular

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9
Q

Water and solutes return to blood stream by moving between tubule cells

A

Paracellular

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10
Q

Water and solutes in tubular fluid pass through a tubule cell to return to blood stream

A

Transcellular

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11
Q

Function of tight junctions in tubule cells

A

Allows solutes to diffuse across them to return to peri tubular capillary

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12
Q

Why does renal tubules have a low concentration of Sodium ions in their cytosol

A

Na/K pump

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13
Q

Where are Na-K pumps located in the renal tubule cells?

A

The Basolateral portion

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14
Q

Lack of Na/K pump in the apical surface ensures what

A

Reabsorption of Na is one way process

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15
Q

Primary active transport

A

ATP is used to pump a substance across a membrane

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16
Q

Secondary active transport

A

Energy stored in an ions electrochemical gradient drives substance across a membrane

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17
Q

Membrane proteins that move two or more substances in the same direction across a membrane

A

Symporters

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18
Q

Move two or more substances in opposite direction across a membrane

A

Anti porters

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19
Q

The upper limit on how fast a transporter can work

A

Transport maximum

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20
Q

Obligatory water Reabsorption

A

Water is obliged to follow the solutes that are absorbed

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21
Q

Facultative water Reabsorption

A

The last 10 percent of water Reabsorption that may be needed

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22
Q

Regulates facultative water Reabsorption

A

ADH

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23
Q

Most solute Reabsorption in the PCT involves this ion

A

Na

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24
Q

How does sodium transport occur in the PCT

A

Symport

Antiport mechanisms

25
Q

Na glucose Symporters

A

Two Na ions

One glucose

Bind to the protein

26
Q

How does glucose molecules leave tubular cell

A

Diffusion

27
Q

When the glucose diffuses it heads to what in the interstitial fluid

A

Peri tubular capillaries.

28
Q

Na/H antiporters

A

H ions are secreted into lumen

Na ions are Reabsorbed to bloodstream

29
Q

Role of carbonic anhydrase

A

Catalyze carbon dioxide and water to make carbonic acid

30
Q

What happens when a secreted H is secreted into tubule

A

It reacts with HCO3 to form carbonic acid

31
Q

Carbonic acid dissociates to form

A

Hydrogen and HCO3

32
Q

What Happens when HCO3 levels rise in cytosol

A

It is diffused back into the blood stream

33
Q

For every H ion secreted into tubular fluid

A

One HCO3 and one Na ion is Reabsorbed

34
Q

Solute Reabsorption of PCT promotes

A

Osmosis

35
Q

Aquaporin

A

Protein in plasma

Membrane that increase rate of water movement across the apical and Basolateral membrane

36
Q

Symporters of thick ascending limb of loop of henle

A

Na , K and two Cl

37
Q

Cells in thick ascending limb of the loop of henle allow for the simultaneous Reabsorption of

A

One K

One Na

Two Cl

38
Q

The distal convuluted tube allows for Reabsorption of

A

Na

39
Q

The DCT allows for secretion of

A

K

40
Q

How is Na Reabsorbed back to the blood stream of DCT

A

Na K pump

41
Q

The return of filtered water and solutes to the blood

A

Reabsorption

42
Q

what is secreted when blood volume and pressure drop

A

Renin

43
Q

what happens to the arterioles when blood volume and pressure drop

A

they are stretched less

44
Q

Renin clips off what from angiotensin

A

angiotensin I

45
Q

Converts angiotensin I to angiotensin II

A

ACE

46
Q

How does Angiotensin II affect renal physiology

A

decreases filtration
enhances reabsorption of Na and Cl
stimulates the release of aldosterone

47
Q

what is aldosterone

A

hormone released by adrenal cortex

48
Q

what is the purpose of aldesterone

A

Causes more reabsorption of Na and CL

49
Q

What is the purpose of more reabsorption of Na and Cl

A

more water is reabsorbed, allowing blood volume and pressure to increase.

50
Q

Releases ADH

A

Pituitary gland

51
Q

Purpose of ADH

A

Increases facultative reabsorption of water

decreases osmolarity of bodily fluids

52
Q

What triggers ADH

A

High blood osmolarity

decreased blood volume

53
Q

Promotes ANP

A

High blood volume

54
Q

Produces ANP

A

Stretching of atrium

55
Q

Purpose of ANP

A

Suppresses​ reabsorption of Na and water in PCT,

decrease blood volume and pressure

56
Q

ANP inhibits

A

Aldosterone and ADH

57
Q

Promotes release of PTH

A

Decreased level of Calcium

58
Q

Releases PTH

A

Posterior Pituitary

59
Q

What does PTH do?

A

Causes reabsorption of Calcium

Urinary System (12 decks)

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