Tubular function 5

Question 1

What is plasma osmolality regulated by

Answer 1

Changes in H20 intake and excretion

Question 2

What is ECF volume regulated by

Answer 2

Changes in NA+ excretion

Question 3

What are changes in effective ECF volume related to

Answer 3

Absolute amounts of Na+ and thus water present

Question 4

What influences ECF osmolality

Answer 4

Thirst

Collecting duct water reabsorption, ADH

Question 5

What influences ECF volume

Answer 5

RAAS
SNS
ANP
Natriuretic factors
ADH
Renal tubula Na+ reabsorption
Water retention

Question 6

What sensors are involved in osmoregulation

Answer 6

Hypothalamic osmoreceptors

Question 7

What sensors are involved in volume regulation

Answer 7

MAcula densa
Renal baroreceptor
Atria
Carotid sinus

Question 8

what is the homeostatic response to salt ingestion

Answer 8

1) ingest salt
2- increase in osmolality
2a- ADH secreted which increases renal water reabsorption

2b- increase in osmolality increases water intake
c- osmolality is returned to normal but salt level is still raised and there is an increase in ecf volume
d- there’s an increase in bp
e - cardiovascular reflexes lower bp
f- ecf volume and bp return to normal
g -kidneys excrete salt and water slowly and osmolality returns to normal