TUBULAR DISORDERS Flashcards

1
Q

TUBULAR DISORDERS

A

Acute tubular necrosis
Fanconi syndrome
Diabetes insipidus
Renal glucosuria

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2
Q

ACUTE TUBULAR NECROSIS

  1. Affected part
  2. Cause
A
  1. Damage to renal tubular cells

2. Ischemia or toxic agents

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3
Q

FINDINGS IN ACUTE TUBULAR NECROSIS

A

Microscopic hematuria
Proteinuria
RTE cells, RTE casts
Hyaline, granular, waxy, and broad casts

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4
Q

ETIOLOGY: Fanconi Syndrome

A

Generalized failure of tubular reabsorption in the PCT

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5
Q

NEUROGENIC vs NEPHROGENIC DI

A

NEUROGENIC - failure of the hypothalamus to produce ADH

NEPHROGENIC - renal tubules fail to respond to ADH

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6
Q

FINDING IN DIABETES INSIPIDUS

A

Low sepcific gravity

Polyuria (>15L/day)

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7
Q

ETIOLOGY: Renal Glucosuria

A

Defective tubular reabsorption of glucose

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8
Q

FINDING IN REANL GLUCOSURIA

A

Glucosuria (Normal blood glucose, increased urine glucose)

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