TRYPTOPHAN DISORDERS Flashcards

1
Q

TRYPTOPHAN DISORDERS

A

INDICANURIA

ARGENTAFFINOMA

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2
Q

URINE DESCRIPTION IN INDICANURIA

A

Indigo blue upon air exposure

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3
Q

INDICANURIA IS SEEN IN

A
  1. Intestinal disorders

2. Hartnup disease

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4
Q

HARTNUP DISEASE IS ALSO KNOWN AS

A

BLUE DIAPER SYNDROME

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5
Q

Test for INDICANURIA

A

OBERMAYER’S TEST

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6
Q

OBERMAYER’S TEST: PROCEDURE + RESULT

A

FeCl3 + Urine + Chloroform = (+) Violet color

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7
Q

What is ARGENTAFFINOMA

A

Tumor of argentaffin/enterochromaffin cells

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8
Q

Function of argentaffin cells

A

Produce SEROTONIN

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9
Q

Metabolite of serotonin

A

5-hydroxyindoleacetic acid (5-HIAA)

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10
Q

SCREENING TESTS FOR ARGENTAFFINOMA (+ RESULTS)

A
  1. FeCl3 tube test: (+) blue green

2. Nitroso-naphthol w/ nitrous acid: (+) violet

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