tubular and interstitial

Question 1

Damage to renal tubular cells caused by
ischemic or toxic agents
-Conditions producing tubular necrosis include
exposure to heavy metals, drug-induced toxicity,
hemoglobin and myoglobin toxicity, viral
infections (hepatitis B), pyelonephritis, allergic
reactions, malignant infiltrations, salicylate
poisoning, and acute allogenic transplant
rejection

Answer 1

Acute tubular necrosis

Question 2

Generalized failure of tubular reaction
in the Proximal Convoluted tubule

Answer 2

Fanconi syndrome

Question 3

A.Neurogenic DI
-Failure of the hypothalamus to produce
ADH
-Low ADH

b. Nephrogenic DI
-inability of the renal tubules to respond to
ADH
-Normal to increase ADH

Answer 3

Diabetes Insipidus

Question 4

Defective tubular reabsorption of glucose

Answer 4

Renal Glucosuria

Question 5

Ascending bacterial infection of the urinary
bladder

Answer 5

Cystitis (Lower UTI)

Question 6

Infection of the renal tubules and
interstitium related to interference of urine
flow to the bladder, reflux of urine from
the bladder (Vesicoureteral reflux)
and untreated cystitis

Answer 6

Acute Pyelonephritis (Upper UTI)

Question 7

Recurrent infection of the renal tubules
and interstitium caused by structural
abnormalities affecting the flow of urine

Answer 7

Chronic Pyelonephritis

Question 8

Allergic inflammation of the renal
interstitium in the response to certain
medication

Answer 8

Acute Interstitial nephritis