glomerular disease Flashcards
Deposition of immune complexes formed in conjunction with group A Streptococcus infection, on the glomerular membranes
Acute Glomerulonephritis
Rapid onset of hematuria and edema. Permanent renal damage seldom occurs
Acute Glomerulonephritis
Deposition of immune
complexes from system
immune disorders on the
glomerular membrane
Rapidly
progressive(crescentic)
glomerulonephritis
Rapid onset with glomerular damage and possible progression to
end-stage renal failure
Rapidly progressive(crescentic) glomerulonephritis
Attachment of cytotoxic
antibody formed during
viral respiratory infections
to glomerular and alveolar
basement membranes
Good pasteur’s
syndrome
Hemoptysis and dyspnea followed by hematuria. Possible progression to end-stage renal failure
Good pasteur’s syndrome
Antineutrophilic cytoplasmic
autoantibody binds to
neutrophils in vascular
walls producing damage to
small vessels in the lungs
and glomerulus
Wegener’s
Granulomatosis
Pulmonary symptoms
including hemoptysis
develop first followed
by renal involvement
and possible
progression to end-
stage renal failure
Wegener’s
Granulomatosis
Occurs primarily in children following viral respiratory infections; a decrease in platelets disrupts vascular integrity
Henoch-Schonleinpurpura
Initial appearance of purpura followed by blood in sputum and stools and eventual renal involvemen. Complete recovery is common, but many progress to renal failure.
Henoch-Schonleinpurpura
Deposition of IgA on the glomerular membrane
resulting from increased levels of serum IgA
IgA nephropathy ( Berger’s disease)
Recurrent macroscopichematuria
following exercise with slow progression to
chronic glomerulonephritis
IgA nephropathy ( Berger’s disease)
Thickening of the glomerular membrane
following IgG immune complex deposition
associated with systemic disorders
Membranous glomerulonephritis
Slow progression to Nephritic syndrome or possible remission
Membranous glomerulonephritis
Cellular proliferation affecting the capillary walls or the glomerular basement membrane, possibly immune mediated.
Membranoproliferative glomerulonephritis
“TRAM TRACKING
PATTERN OF THE
GLOMERULUS”
Noticeable progression to chronic glomerulonephritis to nephritis syndrome.
Cellular proliferation
affecting the capillary walls
or the glomerular
basement membrane,
possibly immune mediated.
Marked decrease in renal function resulting from glomerular damage precipitated by other renal disorders
Chronic glomerulonephritis
Noticeable decrease in renal function
progressing to renal failure.
Chronic glomerulonephritis
Disruption of the
electrical charges that
produce the tightly fitting
podocyte barrier resulting
in massive loss of protein
and lipids
Nephrotic Syndrome
Acute on set following systemic shock Gradual progression from other glomerular disorders and then to renal failure
Nephrotic Syndrome
Disruption of podocytes occurring primarily in
children following allergic reactions and immunizations
Minimal change disease
(Lipid nephrosis)
Frequent complete remission following corticosteroid treatmen
Minimal change disease
(Lipid nephrosis)
Disruption of podocytes in certain areas of glomeruli associated with heroin and analgesic abuse and acquired immunodeficiency syndrome
Focal segmental
glomerulosclerosis
May resemble nephrotic syndrome or minimal change disease.
Focal segmental glomerulosclerosis
