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Coovadias Paediatrics > Tuberculosis > Flashcards

Tuberculosis Flashcards

1
Q

Name reasons for South Africa’s high TB incidence

A

Poverty and rapid urbanisation
HIV pandemic
Poor health infrastructure
Poor program management

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2
Q

Explain a Ghon focus in pulmonary TB

A

Inhaled droplet nuclei lodge in terminal alveoli -> phagocytosed by macrophages -> local immune response = Ghon focus

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3
Q

What is the most common EPTB?

A

TB lymphadenopathy

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4
Q

Discuss TB treatment regimes in children

A

Uncomplicated, smear negative

  • 3 drugs (HRZ) x 2mo
  • 2 drugs (HR) x 4mo

Smear +, cavitatory

  • 4 drugs (HRZE) x 2mo
  • 2 drugs (HR) x 4mo
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5
Q

How do you boost kaletra?

A

Add ritonavir OR

Double kaletra dose

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Coovadias Paediatrics (10 decks)

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