Tuberculosis Flashcards
What bacterium causes TB?
Mycobacterium complex of:
M tuberculosis
M. Bovis
M. Africanum
What is seen on CXR in TB?
Pathy Infiltrate Apical consolidations Contraction of Lobes Cavitation Hilar calcification of lymph nodes
What is IGRA testing and what does it tell us?
Measures the amount of intern gamma from T lymphocyttes
Tells us:
Current have TB
Previous TB
Latent TB
How is TB managed?
Isoniazid
Rifampicin
Pyrazinamide
Ethambutol
What are the side effects of Isoniazid?
Hepatitis
Peripheral Neuropathy
What are the side effects of Rifampicin?
Hepatitis
GI upset
What are the side effects of Pyazinozide?
Anorexia
Flushing
Hepatitis
Arthralgia
What are the side effects of Ethambutol?
Retrobular neuritis (Colour vision at first) Arthralgia
What drugs are used for drug resistant TB?
Fluroquinolone
Amikacin
How do you test for active TB?
Acid fast bacilli - they resist acid on Ziehl Neehlson stain
How do you test for latent TB?
Mantoux test
Inferon Gamma Text
What is a ghon focus?
Subpleural lesion. Related to Mycobacterium