Tuberculosis

Question 1

How is latent TB diagnosed?

Answer 1

A mantoux test or a T-spot test

Question 2

How is active TB investigated?

Answer 2

CXR, sputum samples,

Question 3

How is non-respiratory active TB diagnosed?

Answer 3

clinical sampling of sputum, urine, biopsies for pleura, urine, pus, ascites,

Question 4

What microscopy stain is used for TB?

Answer 4

Ziehl-Neelson stain

Question 5

What are the CXR signs of TB?

Answer 5

Consolidation, calcification, cavitation and collegenatin (fibrosis)

Question 6

What is the treatment of pulmonary TB/

Answer 6

Rifampicin
Isoniazid
Pyrexinamide
Ethambutol

Question 7

What are the side effects of Rifampicin?

Answer 7

Hepatitis + red tears

Question 8

What are the side effects of Isoniazid?

Answer 8

Hepatitis + agranulocytosis

Question 9

What are the side effects of pyrexinamide?

Answer 9

hepatitis +gout

Question 10

What are the side effects of Ethambutol

Answer 10

Optic Neuritis first colour blindness

Question 11

Which systems ) can be affected by TB? give an example of diseases of specific systems

Answer 11

Pulmonary - cough sputum haemoptysis
Skin - lupus vulgaris
Heart - Pericarditis
Neruo - Meningitis 
Bone - vertebral collapse 
GI - peritoneal 
Vasculature - Miliary