Tuberculosis

Question 1

what is the tuberculosis treatment for initial phase? first 2 months

Answer 1

RIPE
-rifampicin
-isoniazid
-pyrazinamide
-ethambutol

Question 2

what is the treatment for the continuation phase which is the 4 months after the first 2?

Answer 2

rifampicin or isoniazid

Question 3

what can be used for latent TB treatment ?

Answer 3

-3 months of rifampicin + isoniazid or 6 months of isoniazid

Question 4

what needs to be checked before treatment for TB?

Answer 4

-Patients with latent TB aged 35-65 YEARS SHOULD BE CLEARED OF HEPATOTOXICITY

Question 5

WHAT ARE THE INTERACTION IWTH RIFAMPICIN?

Answer 5

CYP450 INDUCER
discolours soft contact lenses and bodily fluid orangery-red

Question 6

what are the interactions for isoniazid?

Answer 6

-peripheral neuropathy =give prophylactic pyridoxine hydrochloride (vitamins B6)
-ENZYME INHIBTOR

Question 7

is pyrazinamide heptotoxic?

Answer 7

yes 3 out of the 4 TB drugs are

Question 8

what is counselling for ethambutol?

Answer 8

can cause visual impairment + ocular toxicity

Question 9

how long is treatment for TB?

Answer 9

6 MONTHS UNLESS LATENT AND IT CAN BE 3 MONTHS WITH USE OF 2 DRUGS