Tuberculosis Flashcards
what is tuberculosis
chronic granulomatous disease
what is the causative agent of tuberculosis
Mycobacterium tuberculosis
how is TB transmitted
inhalation of droplets containing Mycobacterium tuberculosis. via coughs
how does tuberculosis survive
after being phagocytosed by macrophages
which group of people are at greatest risk of TB
asian immigrants in the uK
what is primary TB
initial infection may be pulmonary or GI
what is miliary TB
results from haematogenous dissemination of TB
what is post-primary TB
caused by reinfection or reactivation
presentation of primary TB
fever, malaise, cough, wheeze, erythema nodosum, conjunctivitis
presentation of miliary TB
fever, weight loss, meningitis, yellow caseous tubercles spread to other organs
presentation of post-primary TB
Fever/night sweats Malaise Weight loss Breathlessness Cough Sputum Haemoptysis Pleuritic chest pain Signs of pleural effusion Collapse Consolidation Fibrosis
complications of pulmonary tuberculosis
bronchiectasis, pneumonia and pleural effusions
CNS presentation of TB
meningitis, headache, meningism, focal neurological signs, decreased consciousness
genitourinary presentation of TB
pyuria (sterile)
absceses
MSK presentation of TB
arthritis, osteomyelitis