TRYPANASOMA CRUZI

Question 1

3RD CAUSATIVE AGENT

Answer 1

Trypanosoma cruzi

Question 2

DISEASE

Answer 2

Chaga’s disease (American trypanosomiasis)

Question 3

MODE OF TRANSMISSION

Answer 3

bite of reduviid bug

Question 4

CLINICAL PATHOGENIC

Answer 4

The organism attacks cardiac muscles and cause inflammation leading to cardiac arrythmias.

They also damage the nerves controlling the peristaltic action of the esophagus and colon causing MEGACOLON AND MEGAESOPHAGUs

C/F:

The acute phase is consist of facial edema and a nodule (chagoma) near the site of bite

There is fever, lymphadenopathy, hepatosplenomegaly.

Most individials remain asymptomatic but some progress to the chronic form (MEGACOLON AND MEGAESOPHAGUS)
Death is due to cardiac failure.

Question 5

TREATMENT

Answer 5

Nifurtimox

Question 6

PREVENTION

Answer 6

Protection from bite. Insect control