Trigger CKD part 1 Flashcards

1
Q

proteinuric CKD increases risk for what

A

CV mortality

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2
Q

anemia, fatigue, and anorexia begin appearing in what stages of CKD

A

3-4

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3
Q

when do electrolyte abnormalities become present in CKD

A

stages 3-4

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4
Q

marked deceased in ADLs is seen in what CKD stage

A

5

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5
Q

what medication is used to reduce glomerular HTN

A

ACE/ARB

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6
Q

prior to starting this medication, evaluate potassium and serum cr levels

A

ACE/ARB

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7
Q

when in CKD are thiazides most effective

A

early CKD

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8
Q

when in CKD are loops most effective

A

late CKD

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9
Q

what does cholesterol look like in CKD

A

NORMAL

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10
Q

what does HDL and lipoprotein A look like in CKD

A

HDL is deceased
lipoprotein A is increased

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11
Q

when do you use ezetimibe in CKD

A

2nd line for treatment of CAD

“statins - 1st line (said in class)
PSK9 inhibitors and ezetimibe (2nd line in adjunct to statin)
fibrates (paired with statins)”

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12
Q

Cardiovascular complication associated with uremia

A

pericarditis

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13
Q

what is pericarditis associated with?

A

uremic CKD

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14
Q

s/s: friction rub

A

pericarditis

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15
Q

s/s: cardiac tamponade and uremic pericardial efffusion

A

pericarditis

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16
Q

s/s: retrosternal Chest pain

A

pericarditis

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17
Q

what is always an indication of hospitalization and immediate initiation of hemodialysis in CKD patients

A

pericarditis

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18
Q

s/s: proximal muscle weakness

A

osteitis fibrosa cystica

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19
Q

caused by hypovitaminosis D and use of bisphosphonates

A

osteomalacia

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20
Q

brown tumors on Xray

A

osteitis fibrosa cystica

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21
Q

what physiologic changes occur in the heart with CKD

A

left ventricular hypertrophy and diastollic dysfunction

22
Q

SE includes inceased vascular calcification or hypercalcemia

A

calcium carbonate and calcium acetate (calcium phosphate binders for treating hyperphosphatemia)

23
Q

SE of osteomalacia and neurologic complications

A

aluminum hydroxide

24
Q

what phosphate binder is used for short durations (<3 weeks)

A

aluminum hydroxide

25
Q

what phosphate binder is used if phosphate levels are severe (>7)

A

aluminum hydroxide

26
Q

what meds are used to manage PTH in CKD

A

Vit D3 - calcitriol
cincalet (sensipar)

27
Q

SE is inceased serum calcium and phosphorus

A

calcitriol (vit d3)

28
Q

SE of hypocalcemia

A

cincalet

29
Q

deceased renal clearance of hepcidin in CKD leads to what complication

A

iron deficiency anemia

30
Q

when is treatment of iron deficiency anemia contraindicated

A

if ferritin levels are >500-800 even if iron saturation is <20%

31
Q

when is ferric citrate used

A

treatment of iron deficiency anemia in CKD

can also use:
ferrous sulfate
ferrous gluconate
ferrous fumerate but ferric citrate was bolded in powerpoint

32
Q

what complication in CKD is caused by platelet dysfunction

A

hypocoagulability

33
Q

treated with desmopressin

A

hypocoagulability

34
Q

s/s: difficulty concentrating

A

ealry uremic encephalopathy

35
Q

s/s: lethargy, confusion, seizure coma

A

later uremic encephalopathy

36
Q

PE: asterixis, weakness, AMS

A

uremic encephalopathy

37
Q

TCAs or anticonvulsants are given for pain in this complication

A

uremic neuropathy

38
Q

when do you start hemodialysis or peritoneal dialysis

A

GFR of 5-10

39
Q

what 4 signs are indications of need for dialysis in CKD patients

A
  • GFR<10
  • Uremic symptoms (pericarditis, encephalopathy, neuropathy)
  • metabolic disturbances (hyperkalemia, hyponatremia, met acidosis, ect)
  • fluid overload unresponsive to diuretics

(i just cant get this into my brain)

40
Q

at what point in CKD should you STOP metformin use?

A

serum Cr>1.5 or GFR <30

remember if a CKD pt is struggling with hypoglycemia in CK we can start them on

41
Q

petechiae and purpura are s/s of what complication in CKD

A

hypocoagulability

42
Q

can be caused by NSAIDS and BB

A

hyperkalemia

43
Q

Triamterine SE is…

A

hyperkalemia

44
Q

what vascular access option for hemodialysis requires 6-8 weeks of preparation

A

arteriovenous fistula

45
Q

what vascular access option for hemodialysis requires 2 weeks for preparation and has a higher risk of infection

A

prosthetic graft

46
Q

what vascular access option for hemodialysis is temporary and has the highest risk of infection

A

indwelling vascular catheter

47
Q

what are examples of phosphorus containing drugs to avoid in CKD

A

cathartic laxatives

48
Q

what are examples of magnesium containing drugs to avoid in CKD

A

laxatives/antacids

49
Q

what are examples of nephrotoxic drugs to avoid in CKD

A

NSAIDS, IV contrast

50
Q

what are examples of renally excreted drugs to adjust in CKD

A

insulin, BB, ABX

51
Q

what opioid should be stopped in CKD

A

morphine

52
Q

cloudy dialysate indicates what

A

peritonitis