Tricuspid Regurgitation Flashcards
What is involved in the tricuspid valve complex? 5
- TV annulus
- Three leaflets
- Chordae tendinae
- 2 discrete pap muscles
- RV myocardium
What are the three leaflet tips of the tricuspid valve? 3
- Septal
- Anterior
- Posterior
What are the three TV commissures? 3
- Anteroseptal commissures
- Anteriorposterior commissures
- Posteroseptal Commisure
Where is the anterioseptal commissures located?
Between the anterior and septal leaflets
Where is the anteroposterior commissure located?
Lies between the anterior and posterior leaflets
Where is the posteroseptal commissures located?
Lies between the posterior and septal leaflets
What are some clinical features of TR? 3
- Usually well tolerated
- Severe/ progressive TR may show signs of right sided heart failure
- May show clinical features of underlying cardiac conditions
What are some clinical features of ECG/ EXR for TR? 3
- RA enlargement
- A-Fib
- RBBB
What are some clinical features of auscultation for TR?
Holosystolic murmur along LT sternal border
What is the role of echo to assess TR? 5
- Determine etiology of the lesion
- Assess RA size
- Assess RV size and function
- Estimate severity of the regurgitation
- Estimate right heart pressures
What is tricuspid regurgitation?
The backward flow of blood from the RV and the RA during systole due to an incompetent TV
Etiology of TR can be divided into 3 subgroups, what are they? 3
- Functional (secondary) causes
- Organic primary causes
- Mechanical causes
As with MR, TR may occur due to what?
Disorders affecting any part of the TV complex
What are some examples of functional causes of TR? 6
- Atrial fibrillation
- Atrial septal defect
- Pulmonary hypertension
- Dilated cardiomyopathy
- RV CHF
- RV infarction
What are functional causes?
Any thing that causes annular dilation
What are organic causes?
Disorders of the TV complex
What are some organic causes examples? 4
- Carcinoid heart disease
- Infective endocarditis
- Epstein anomaly
- Trauma
What are some examples of mechanical causes?
Pacemaker leads
Rheumatic TV disease almost never occurs when/ where?
In isolation
What is almost always involved with rheumatic TV disease?
MV
Rheumatic TV disease is characterized by what?
Thickened and retracted TV leaflets
What is seen with the TV in 2D when there is rheumatic TV disease?
Diastolic doming
Besides the thickened and retracted TV leaflets what else may happen to the annulus?
Dilation May occur
What is a carcinoid heart disease?
When there is a rare malignant tumour which damages right heart valves
What happens to the TV with carcinoid heart disease?
The TV becomes thickened, retracted and rigid
What does carcinoid heart disease lead to?
TS and TR
With carcinoid heart disease, how is the valve of the TV?
The valve remains in a fixed semi-open position throughout the cardiac cycle
What is the key difference between carcinoid and rheumatic heart disease?
The involvement of the MV/AV with Rheumatic
What does aliasing during systole and diastole indicative of during carcinoid HD?
MS and MR
What disease has thickened, retracted TV leaflets and normal MV mobility?
Carcinoid HD TR
What happens with traumatic TV rupture?
Trauma puts extreme pressure on the TV chordae
The RV is more easily what? What does this lead to?
Compressed than LV, making TV more susceptible to rupture
Traumatic TV rupture may lead to what?
Chordal rupture or flail leaflet
What would be an example of acute TR with flail?
Traumatic TV rupture
What is TVP or Tricuspid valve prolapse?
Systolic bowing of the belly of the leaflets into the RA during systole?
What does TVP normally occur with?
In association with MVP
What is Epstein anomaly?
Malformation of the TV leaflets during development leading to them being placed higher up on the RV
What are the four major characteristics of Ebstein anomaly? 4
- Apical displacement of the septal leaflet
- Atrialization and dilation of a portion of the RV inflow tract
- Small functional RV
- “Struck” septal/posterior leaflets
What is ebstein anomaly associated with? 4
- PFO/ ASD
- L-TGA
- VSD
- Hypoplastic pulmonary artery
Epstein may lead to maldevelopment of what?
The conduction pathway from atria to ventricle.
What syndrome may ebstein lead to eventually?
Wolfe-Parkinson’s white syndrome
What view should we use to view ebstein anomaly?
A4C view
Ebstein s can be diagnosed when the septal TV leaflet is displaced how much apically?
> 2cm
During Ebstein anomaly, which leaflet may have restricted motion?
The anterior TV leaflet
Which leaflet may have a whiplike motion and be longer with redundant tissue, in terms of Ebstein anomaly?
Septal TV leaflet
When we assess ebstein with colour, how will it present? why?
There will invariably be some degree of TR due to lack of coaptation
When we use spectral doppler to interrogate Ebstein what might we see? 2
- ASD or PFO with colour in colour or pulsed wave doppler
- Shunt direction being right to left instead of left to right
What is eisenmenger’s syndrome?
When the shunt direction reverses from being left to right to right to left
What does PFO stand for?
Patent foramen ovale
What is a functional cause of TR?
Annular dilatation
What is ASD or atrial septal disease?
A birth defect of the heart in which there is a hole in the wall (septum) that divides the chambers (atria) of the heart
Why do we have have TR with annular dilation?
The atria gets so big that the leaflets can’t touch.
How are the TV leaflets with annular dilation?
They are normal and fully functional
What are common causes of annular dilation? 3
- Dilated cardiomyopathy
- Atrial septal defect
- Pulmonary hypertension
How does Pulmonary hypertension lead to functional TR?
PHTN leads to RV dilation then functional TR
How does RV dilation affect the TV? 2
- Incomplete coaptation of the TV leaflets
- Pap muscles pulled artery from TV
TR peak velocity does not reflect on what?
The velocity of the TR but simply the pressure difference between RV and RA during systole
With pulmonary hypertension, What does TR look like? 2
- Mild TR with high jet velocity
- Severe TR with Low jet velocity
What does paradoxical septal motion look like with PAH and TR?
The IVS looks flat because the high RV pressure is pushing it to the LT side in a “shape”
PAH and TR can be caused by what two things? 2
- RV volume overload
- RV pressure overload
What does a RV volume overload look like
D sign only during diastole
What does RV pressure overload look like?
D sign throughout the entire cycle
How do we determine the RA size?
RA volume index
What is the RA volume index numbers for Male and female? 2
- Male: 32 ml/m
- Female 27ml/m
What is the normal range for TAPSE
> 17mm
What is the S prime normal value?
> 9.5 cm/s
What normal FAC ranges?
> 35%
What is normal RIMP values?
<0.44
What are three ways to estimate severity of Regurgitation? 3
- Qualitative assessment
- Semi-qualitative assessment
- Quantitative assessment
What are some examples of qualitative assessment? 3
- Colour jet area
- Vena Contracta width
- Flow convergence radius
What are some examples of semi-qualitative assessment? 4
Spectral doppler
1. Tricuspid inflow PW
2. Hepatic vein profile PW
3. Intensity of TR signal CW
4. TR jet contour CW
What quantitative assessment examples? 2
- Regurgitation volume (RV)
- Effective Regurgitant orifice area (EROA)
What the Mild, moderate, severe values for TR jet area measurement? 3
- Mild <5cm
- Moderate 5-10cm
- Severe >10cm
How often is TR jet area measurements taken?
Still performed in some labs but not common
How do we get TR jet area measurements?
Trace around the aliased portion of the TR jet only using the calc package.
trace only the aliased jet to avoid overestimation
How many planes should we use for TR jet area measurement?
Multiple planes
Label the regurgitation? 3
- Mild central
- Several Central
- Severe Eccentric
When do we have an underestimation of TR jets?
When there is an eccentric jet
What does the Coanda effect?
When there is an eccentric jet that will hug the atrial wall
What happens when there is a severe lack of TV coaptation?
A huge hold in the TV during systole is formed
When there is a huge hole in the TV during systole due to a lack of TV coaptation, is there Aliasing and why?
No aliasing due to the low velocity of the TR jet.
What does TR jet velocity represent?
The pressure gradient between RV and RA
Label the image?
What are the valves for Vena contracta and PISA radius? Know the PISA radius numbers VC is a bonus
Same as MR
Can we use Vena contracta and PISA if there are multiple jets?
No
What is a tip for measuring Vena contracta?
Zoom on any window
PISA should be measured in which view?
A4C with zoom
What should the Nyquist limit be set for PISA radius?
20-40 cm/s
In terms of TV inflow pulsed wave doppler, the E and A wave velocity should be lower than what?
MV
What might >1.0 m/s indicate when interrogating for a TV inflow PW doppler?
Severe TR
What should Normal TV flow be?
0.7 m/s
When two volumes are combined what happens in the TV?
Regurgitant volume increases, but for this to happen more flow must travel through the TV
What happens when there is less forward flow into the IVC due to TR?
The liver becomes engorged
TR signal intensity depends on what?
The number of RBCs moving in the same direction
More/ Less RBCs mean what in terms of waveform?
More = brighter TR signal and vice versa
What re some technical factors we might need to consider when looking at the intensity of TR doppler signals? 2
- Gain
- Doppler angle
What do we need to compare in terms of TR brightness when adjust gain?
Antegrade flow
Label the image
With Mild TR, The high PG is affected how?
It is maintained throughout systole
What is the appearance of mild TR?
Parabolic appearance
What is the appearance of significant TR?
Triangular cutoff or V cut off
With significant TR, The PG does what?
Reduces as the TR enters the RA during systole
What happens in the Hepatic vein when there is severe TR?
Systolic reversal
What are the two main methods used to quantify the amount of regurgitation using the PISA principle? 2
- Regurgitant volume
- EROA (effective Regurgitant orifice area)
What are ways we can estimate right heart pressures? 4
- RVSP
- PAT
- mPAP
- PAEDP