Aortic Regurgitation Flashcards
What is Aortic insufficiency?
Aortic regurgitation
What happens during aortic insufficiency?
Blood moves backwards through the AV from aorta to the left ventricle throughout diastole
What are the 3 groups of mechanisms that can cause AI? 3
- Cuspal abnormalities
- Aortic root dilatation
- Loss of commissures support
Cuspal abnormalities include what? 4
- Congenital abnormalities
- Rheumatic aortic valve disease
- Aortic valve prolapse
- Infective endocarditis
What is Cuspal abnormalities in general?
Any congenital disorder or disease process that affects the AV cusps
What are things we should look for in terms of congenital abnormalities? 2
- Bicuspid AV
- Quadricuspid AV
Wha this Rheumatic AV disease?
Cusp tissue is infiltrated wit fibrous tissue causing them to shorten and retract
What can no longer happen during rheumatic AV disease?
Cups can no longer come together to coapt
Rheumatic AV disease is usually associated with what?
Some degree of Aortic stenosis
How common is aortic valve prolapse?
Rare
What is Aortic valve prolapse defined as?
Cusp leaflet tips displaced below the valve ring during diastole
Aortic valve prolapse maybe due to what? 2
- Myxomatosis degeneration of the valve or due to rheumatic heart disease
- Occur secondary to aortic root dilation or trauma
What is aortic bacterial endocarditis?
Vegetation destroys the AV
What may Aortic bacterial endocarditis may cause?
Perforation of the cusp
What does aortic root dilation prevent?
Normal leaflet coapt action during diastole which leads to AR
What are causes of Aortic dilation? 6
- HTN
- Atherosclerosis
- Connective tissue disorders
- Bicuspid AV
- Sinus of valsalva aneurysm
- Idiopathic dilation
Loss of commissures support may occur with what? 3
- Ventricular septal defects
- Aortic dissections
- Aortic trauma
What are some causes of severe AR? 3
- Trauma
- Infective endocarditis
- Aortic dissection
Acute- severe AI causes an increase in what?
Filling pressures
Mainly LV end diastolic pressure
What is this hole in the AV caused by?
Annular dilation
Why is Acute severe AI mainly in the LVEDP? 2
During diastole we have
1. Normal inflow plus
2. Regurgitation volume leaking back into the LV
During LVEDP Acute means what in terms of acute severe AI?
No time for LV to stretch, therefore LVEDP increases dramatically
What is chronic severe AI pressure?
Filling pressure normal and slightly elevated
In terms of chronic severe AI regurgitation volume causes what?
LV chamber volume to increase over time due to stretching