Trichomonas Vaginalis Flashcards

1
Q

What is the host for T. Vaginalis ?

A

Man

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2
Q

What is the mode of infection?

A

Vaginal sexual intercourse

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3
Q

What is the multiplication?

A

Binary longitudinal fission

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4
Q

What is the habitat for T. Vaginalis for female and male?

A

Female: vagina
Male: urethra, epididymis, prostate

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5
Q

How does it move (motility)?

A

Flagella and undulating membrane

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6
Q

What diseases can it cause?

A

vaginitis, urethritis, prostato-vesiculitis

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7
Q

What is the transmission?

A
  1. vaginal sexual intercourse
  2. sharing douche equipment
  3. during passage in birth canal in newborns
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8
Q

What is it frequently coexistent with ?

A

candidiasis gonorrhea
syphilis
HPV or HIV etc

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9
Q

Why does T. Vaginalis does not appear to have a cyst form?

A

Because it does not survive in the external environment.

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10
Q

What is the infective and invasive form?

A

Trphozoite only

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11
Q

Describe the life cycle.

A
  1. Trichomonas vaginalis reside in the female lower genital tract and the male urethra and prostate where it replicates by binary longitudinal fission.
  2. It is transmitted among humans primarily by sexual intercourse
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12
Q

What pH of vaginal does it requires?

A

5 - 5.5

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13
Q

Explain the pathogenesis of “strawberry cervix” cause by Trichomonas Vaginalis.

A

Trophozoite is invasive.
Trophozoite burrows in vaginal epithelium.
It has no penetration power so it does not pass to sub-epithelial layer.
Causes degeneration and desquamation of vaginal epithelium.
Followed by leukocytic inflammation with very large number of trichomonas and leukocytes.
Causes inflammation with hyperaemia and petechial hemorrhage (strawberry cervix)

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14
Q

What is the symptoms in female?

A

1.Vaginitis with foul smelling, frothy, purulent, creamy
or yellowish discharge
2. Onset of vulvapruritis (itching of vulva)

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15
Q

What is the symptoms in male?

A

frequently asymptomatic,
occasionally urethritis, epididymitis and prostatitis

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16
Q

What is expected diagnosis of Trichomonas vaginalis for females by speculum examination?

A
  1. frothy, seropurulent (serum+pus) creamy/yellowish (speculum)
  2. punctuate lesion at the vagina & cervix
  3. hyperaemia of vagina
17
Q

what is expected microscopis examination on vaginal discharge - wet mount (collected from posterior fornix)?

A
  1. actively motile parasite is seen
  2. stain with Giemsa
18
Q

How to diagnosis T. Vaginalis in male?

A
  1. examine the prostatic secretion urine
  2. Use direct immunofluorescent antibody staining
19
Q

What is the treatment for both male and female?

A

oral metronidazole

20
Q

How to prevent T. Vaginalis infection?

A

avoidance of sex with infected persons, avoid sexual promiscuity (dgn sembarangan orang) and personal hygiene

21
Q

For AIDS patient, is it possible to perform serology or PCR of parasite DNA?

A

No. Because AIDS patient has reduced antibody production.