Trematodes Flashcards
Trematodes are also known as
Flukes
Trematodes general morphology
Leaf shape
Ventral side is flat
Dorsal side is convex
Hold fast organs of trematodes
Suckers
Trematodes have (complete,incomplete) digestive tracts
Incomplete
*No anal opening, undigested food regurgitates to oral opening.
*ability to absorb nutrients thru teguments
Reproduction of trematodes (sexual, asexual)
BOTH
1st intermediate hosts of trematodes
Snails (mollusks)
T/F: All trematodes requires 2 intermediate hosts
False. Schistosoma only requires 1 (snail)
Trematode that is not hermaphoditic/monoeious
Schistosoma
(Separate male and female adults)
T/F: Schistosoma have operculated eggs
FALSE.
All trematodes except schistosoma has
General pattern of trematodes life cycle
Adult - egg - miracidium - 1st intermediate host - cercaria - metacercaria - adult
Trematode’s definitive host
Human
Trematode: Miracidium infects _______
Suitable 1st intermediate host (mollusks)
Trematode: cercaria will infect __________
2nd intermediate host (snails, crabs, vegetation)
Trematode: inside the 2nd intermediate host, which will form a cyst in the tissue
Metacercaria
The most important genus of medically significant trematodes
Genus Schistisoma
Blood flukes
Genus Schistisoma
Genus Schistisoma are (homoemicious, diemicious)
Diemicious
The most important specie of Schistisoma
Schistisoma japonicum
Oriental blood fluke
S. Japonicum
Schistisoma spp that is found in mesenteric veins
S. Japonicum
The life cycle of S. Japonicum will only be complete if it will be…
Shed from the body of the definitive host
S. Japonicum will be acquired by humans if…
There is contact with infected water
*cercaria will attach and penetrate the intact skin then reach the blood vessels, reach portal circulation and mature into adults
In terms of morphology, S. Japonicum male are more ________, while female are ______
Robust; slender and longer
During copulation of S. Japonicum, female rest on _________
Gynecopherol canal on ventral region/side of male adult
Clinical manifestations of S. Japonicum
Swimmer’s itch
Katayama fever/Snail fever
Bilharziasis (chronic)
Diagnosis of S. Japonicum
Eggs in biopsy (INC sensitivity) or stool (often negative)
Circumoval Precipitin Test (COPT)
ELISA
Indirect Hemagglutination
**Immunodiagnosis common in Ph
Trematode found in South America, Central Africa
Schistosoma mansoni
Describe the eggs of S. Mansoni
Has large thorn-like/rose thorn-like lateral spine
In humans, S. Mansoni is found on
Mesenteric veins of the lower colon
S. Haematobium is geographically found in….
the continent of Africa
Differentiate the eggs of S. Haematobium and S. Mansoni
S. Mansoni has a spine located laterally while S. Haematobium’s spine is found terminally
In humans, S. Haematobium is foun in…
Prostatic and uterine plexuses (around urinary bladder)
Which Schistosoma spp requires a urine sample for diagnosis?
S. Haematobium
Schistosoma mekongi is found geographically in…
South east asia in the Mekong River basin
S. Intercalatum eggs are similar to S. Haematobium but it has…
Curved terminal spine (subjective)
T/F. S. Intercalatum can be detected on both feces and urine
True
Paragonimus westermani:
1st intermediate host: _________
2nd intermediate host: __________
1st: Snail
2nd: Crustaceans *Depend on geographical location (prawn, crayfish, crab)
P. Westermani is acquired through ingestion of..
Raw/insufficiently cooked crabs
P. Westermani adults are found in…
Lungs of definitive host = produce ova
P. Westermani eggs/ova passed in…
Sputum or feces
Adult fluke looks like coffee bean is…
P. Westermani (7-12mm)
P. Westermani diagnosis, usually detected in feces are…
Ova
Describe the ova of P. Westermani
Flat operculum, abopercular thickening, tapered,
Clinical manifestations of P. Westermani
Pulmonary diseases
Symptoms when infected with P. Westermani may be mistaken as…
Pulmonary tuberculosis
- chronic cough
Rust colored sputum
Hemoptysis
Similar chest x-rays
To differentiate P. Westermani infection and Pulmonary tuberculosis use…
P-Tb - acid fast bacili
P. Westermani - ova in sample
Giant intestinal fluke
Fasciolopsis buski
F. Buski adults found in…
Small intestine
2nd intermediate host of Fascilopsis buski
Aquatic plants (e.g. Kangkong, water chestnut)
*Water chestnut floats in rivers/lakes = seeds eaten raw
Diagnostic stage of F. Bruski
Egg/ova
F. Bruski is difficult to differentiate from..
Fasciola
To differentiate Fasciola and Fasciolopsis identify the…
Infected body site
Fasciola: Liver
Fasciolopsis: Intestine
Echinostoma ilocanum and Artyfechinostonum malayanum’s 2nd intermediate host: _______
Snails
E. Ilocanum and A. Malayanum can be acquired through…
Ingestion of snails
PH: Pomacea caniculata (Golden Kuhol)
T/F: A. Malayanum demonstrates collar spines
FALSE: Adult E. Ilocanum demonstrates collar spines
Number of testis of E. Ilocanum
2
Diagnosis of E. Ilocanum/A. Malayanum
Eggs in stool
Flukes found in Japan
Heterophyid Flukes
2nd intermediate host of heterophyid flukes
Fish
Parasite of fish eating hosts
Heterophyid flukes
Heterophyid flukes species
Heterophyes heterophyes
Metagonimus yokogawai
Haplorchis taichui
Haplorchis yokogawai
Heterophyes has ____ acetabulum
Metangonimus has __ acetabulum
3 (3rd: genital sucker)
2
Manifestations of heterophyid flukes
Inflammation and excessive mucus production
Eggs and adults found in ectopic sites (occasionally)
Damage to intestinal tract
Fasciola hepatica and Fasciola gigantica are infections in…
Liver
Liver flukes
Sheep: F. Hepatica (temperature liver fluke)
Giant liver fluke - F. Gigantica (tropical liver fluke)
2nd intermediate host of Fasciola spp
Aquatic Plants
SImilar to F. Bruski
Adult of what trematode has a cephalic cones (triagular shape in anterior end)
Fasciola spp.
Hepatomegaly is a clinical manifestation of which trematode
F. Hepatica, F. Gigantica (fasciola spp)
Halzoun is manifested by which trematode
Fasciola spp.
suffocation due to temporary lodging of worm in the pharynx brought by ingestion of RAW liver
Eggs in bile may be diagnostic for…
Fasciola spp
T/F: Eggs in stool may be result of ingesting cooked liver but does not cause infection
True
Chinese liver flukes
Clonorchis sinensis
Cat liver fluke
Opisthorcis felineus
Differentiate adult morphology of Clonorchis and Opisthorchis
Clonorchis: branched testis
Opisthorchis: Lobed testis (2 lobes)
Associated with liver and bile duct carcinoma
Clonorchis and opisthorchis
Oriental lung fluke
P. Westermani
Smallest trematode
Heterophyid flukes
Largest trematode that produces disease
Fasciola spp.