Treatments Flashcards
What are the two different therapies for SZ?
CBT
Family therapy
What is used in drug therapy?
antipsychotics
What are the two types of antipsychotic drugs?
typical antipsychotic
atypical antipsychotic
Which antipsychotic is first generation?
Typical
Which antipsychotic is second generation?
atypical
What happens if typical antipsychotics don’t clear up symptoms?
Move into atypical antipsychotics
Example of typical antipsychotics?
Chlorpromazine
What is Chlorpromazine?
a dopamine antagonist
What does dopamine antagonist mean?
Reduce levels of dopamine activity within the brain
How does chlorpromazine work?
Binding to the D2 receptors on the post synaptic neuron
What does a reduction of dopamine mean for SZ symptoms?
Reduce positive symptoms (hallucinations)
What is chlorpromazine also used as?
A sedative
Example of atypical antipsychotics?
Clozapine
What is clozapine?
Dopamine antagonist
Serotonin agonist
What does serotonin agonist mean?
Increase levels of serotonin in the brain
How does Clozapine work?
binds to D2 dopamine receptor sites on the post synaptic neuron
Act as agonist upon serotonin receptor sites (2A and 2C)
What does an increase of seretonin mean for SZ symptoms?
Reduces negative symptoms such as reducing low mood and avolition
Difference between atypical and typical antipsychotics?
Atypical psychotics can be used to treat both positive and negative symptoms WHEREAS typical only treats positive symptoms
Why are typical antipsychotics used first?
Atypical antipsychotics are associated with a life threatening illness
What illness are atypical antipsychotics associated with?
Agranulocytosis
What is agranulocytosis?
Blood condition where there are low levels of white blood cells
What is bad about low levels of white blood cells
limits an individuals ability to fight disease and illness
Aim of CBT with sz?
Help patients identify irrational/delusional thoughts, change them to more rational ones
What happens once the irrational thought has been identified in CBT?
The psychiatrist would challenge the patients irrational thoughts in order to encourage patients to come up with more plausible explanation