Treatment of Restrictive Lung Diseases

Question 1

These drugs are approved for patients with mild,
moderate and severe IPF?

Answer 1

❑Nintedanib (Ofev®)
❑Pirfenidone (Esbriet®)

Question 2

Mechanism of action:
❑Pirfenidone

Answer 2

• inhibits transforming growth factor beta

Question 3

Mechanism of action:
❑Nintedanib

Answer 3

• Inhibits RTKs

Question 4

Drugs to Reduce Inflammation

Answer 4

❑Corticosteroids
❑Immunosuppressants
•Azathioprine
•Cyclophosphamide
•Mycophenolate mofetil