Hypothalamic & Pituitary Gland Disorders

Question 1

Obese hypertensive lady with hypopituitarism, enlarged sella pituitary gland height loss

Answer 1

Empty sella syndrome

Question 2

Headaches, blurring of peripheral vision, sudden hypopitutarism

Answer 2

Pituitary apoplexy

Question 3

Failure of migration of neurons olfactory to hypothalamus»»Delayed puberty, Testis is <1-2 mL volume & ANOSMIA GnRH def

Answer 3

Kallman syndrome

Question 4

Abnormalities in growth hormone receptors (GHR) due to mutations Low GH & IGF-1 low

Answer 4

Larron syndrome

Question 5

Any blood disorder that can cause pituitary infarction

Answer 5

SCD

Question 6

Stunted growth, increased body fat decreased muscle mass

Answer 6

GHRH

Question 7

Increases prolactin

Answer 7

Dopamine block and high TRK, Prolactinoma

Question 8

Bitemporal hemianopsia

Answer 8

Optic chiasm compression

Question 9

Fatigue, dizziness, weight loss, reduced muscle mass/muscle weakness, low blood sugar and low blood pressure

Answer 9

Low ACTH

Question 10

Cold intolerance, wight gain, brittle nails & hair irregular menses, decreased growth in children

Answer 10

TRH

Question 11

Galactorrhea loss of lateral vision H/A

Answer 11

Prolactinoma

Question 12

Grossly machine oil like secretions seen

Answer 12

Craniopharyngioma

Question 13

Child, brain tumor squamous cells seen on histopathology

Answer 13

Craniopharyngioma

Question 14

Pituitary tumor Tumous shows GNAS mutation IGF RAISED

Answer 14

Somatroph adenoma GH

Question 15

Tumor is a derivative of Rathkes pouch Child Calcified tumour

Answer 15

Craniopharyngioma

Question 16

Pt on Haloperiodol What clinical symptom expected, Why??

Answer 16

Increase prolactin dopamine antagonist