Treatment of Large Animal Wounds Flashcards
Wound healing has 3 overlapping stages…. what are they?
Inflammatory phase
Proliferative phase
Remodeling phase
What occurs during the inflammatory phase of healing?
Vasoconstriction for hemostasis
Vasodilation
Formation of provisional wound matrix
Cellular response
how long does the inflammatory stage last for?
0-3 days
How long does the proliferative phase last for?
2-14 days, usually active by day 3
What is the main objective of the proliferative phase?
protection of the wound surface by formation of granulation tissue & new epithelium
What is the purpose of angiogenesis?
To restore oxygenation & supply nutrients to granulation tissue
What is important to remember about granulation tissue?
It does NOT have nervous innervation
When does the remodeling phase begin?
Around day 7+
What percentage of final wound strength is achieved in the first 3 weeks?
- 20%
How long can scar formation take?
up to 2 years
Which heals better, ponies or horses? Why?
ponies - due to the differences in local inflammatory response & functional capacity of leukocytes
What are the 4 ways of classifying a wound based on contamination?
- Clean
- Clean-contaminated
- contaminated
- dirty or infected
What is a clean wound?
- surgical incisions made under aseptic conditions
- primary closures
What is a clean-contaminated wound?
Surgical incisions made to involve the respiratory, GI, or urogenital tracts entered under controlled conditions
What are contaminated wounds?
open wounds
Traumatic wounds
Sx incisions w/ major breaks in asepsis
What are dirty or infected wounds?
Exudative
Traumatic wound w/ delayed txt
Obvious contamination
Devitalized tissue present
What are examples of open wounds classified by type?
incisions, erosions, lacerations, burns, abrasions, punctures
What are examples of closed wounds classified by type?
bruises, hematomas, contusions
When classifying a wound based on bacteria, what are the options?
clean, clean-contaminated, contaminated
Dirty or infected
When classifying a wound based on time, what are the options?
Class 1 - < 6 hrs w/ minimal contamination
Class 2 - 6-12 hrs w/ significant contamination
Class 3 - >12 hrs w/ gross contamination
What sedative would you use when trying to assess wounds?
alpha-2 agonist & opioids
When do you take a swab for culture & sensitivity for wound management?
before you clean OR if its very contaminated, clean the outer aspect of the wound then lavage w/ sterile saline before swabbing deep
Determine the extent of wound by…
- probing/sterile gloved finger
- assess for damage to vital structures
- assess for foreign bodies, sequestrate, etc
What are some general considerations during wound management?
- Owner’s goals
- treat or refer?
- wound closure
- antibiotics, anti-inflammatories, TAT, or toxoid
- what type of dressing or bandage?
- box rest?
What type of local anesthetic can be used?
distant perineural nerve blocks
ring or splash blocks
What is the duration of action of lidocaine?
90-180 mins
What is the duration of action of mepivacaine?
120-180 mins
What is the duration of action of bupivicaine?
180-500 mins