Treatment in psychiatry Flashcards

1
Q

SSRI S/E

A
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2
Q

Serotonin syndrome S/E

A
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3
Q

Antidepressant

9 classes

A
  1. Selective serotonin reuptake inhibitor (SSRI)
  2. Serotonin noradrenergic reuptake inhibitor (SNRI), eg. venlafaxine, desvenlafaxine, duloxetine
  3. Noradrenaline and dopamine reuptake inhibitor (NDRI), eg. bupropion
  4. Selective noradrenergic reuptake inhibitor (NRI), eg. reboxetine
  5. Serotonin antagonist and reuptake inhibitor (SARI), eg. trazodone
  6. Noradrenaline antagonist and selective serotonergic antidepressant (NaSSA), eg. mirtazapine
  7. Melatonin receptor agonist, eg. Agomelatine
  8. Tricyclic antidepressants (TCAs) eg. amitriptylline, clomipramine
  9. Monoamine oxidase inhibitor (MAOI), eg. Moclobemide
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4
Q

Antipsychotics
Dopamine pathways

A
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5
Q

Dopaminergic side effects

A
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6
Q

EPSE types

A
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7
Q

Acute dystonia EPSE

Features
Treatment

A
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8
Q

Parkinsonism EPSE

Treatment

A
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9
Q

Akathisia EPSE

Feature
Treatment

A
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10
Q

Tardive dyskinesia

Feature
Treatment

A
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11
Q

Neuroleptic malignant syndrome

Features
Treatment

A
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12
Q

Non-dopaminergic side effects anti-psychotics

A
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13
Q

Mood stabilizer

Types

A
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14
Q

Lithium

Pre-treatment preparation
Monitoring timing
On treatment monitoring
Discontinuation method

A
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15
Q

Lithium C/I

A

DDI- Diuretics- NSAID- CCB- ACEi

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16
Q

Lithium S/E

17
Q

Lithium toxicity
Level
Management

18
Q

BZD types

19
Q

BZD side effects

20
Q

BZD

Tolerance and withdrawal and toxicity management

21
Q

Pregabalin

S/E

22
Q

Z drug
MoA

S/E

A

MOA
- Binds selective to BZ1 subtype GABA-receptors
- Facilitate GABA-mediated chloride influx and neuronal inhibition
- Antagonised by Flumazenil (competitive antagonist of binding site)

Special SE:
- Zolpidem: Sleepwalking
- Zopiclone: Methaemoglobinaemia

23
Q

Buspirone

MoA
ADR
DDI

24
Q

MAOI

MoA
ADR
Caution with which food and drugs

25
Q

TCA

MoA
ADR

A

Tricyclic/ Tetracyclic Antidepressants (TCA) Psychiatry e.g. Amitriptyline, Clomipramine, Imipramine, Nortriptyline, Prothiaden

26
Q

SSRI

Types
Which has least DDI

27
Q

SSRI

ADR
DDI

28
Q

NRI/ NDRI/ SNRI/ SARI examples

29
Q

NASA example

30
Q

MRA
example
Special SE

31
Q

SSRI

Specific receptor types SE

32
Q

Specific ADR of TCA, SARI, NASA, SNRI, MRA

33
Q

Valproate

MoA
ADR
DDI

34
Q

Lamotrigine

Use
ADR
DDI

35
Q

Carbamazepine

ADR

36
Q

Mood stabilisers in pregnancy

37
Q

Compare FGA and SGA

38
Q

Antipsychotic

Specific receptors and SE

39
Q

EPSE

Types

Mx