Treatment Flashcards
What is the treatment of choice for stage I and most stage II NSCLC?
Surgery
Whipple
Pancreaticoduodenectomy
Removal of distal portion of stomach, 1st & 2nd portions of duodenum, head of pancreas, CBD, and gall bladder
What are common chemos for endometrial cancer?
Paclitaxel, doxorubicin, cisplatin
What is treatment for low grade nonseminoma or high grade testicular cancer?
BEP
bleomycin, etoposide, cisplatin
What is treatment for low grade seminoma testicular cancer?
Surveillance or radiation or Adjuvant Carboplatin
What is the treatment for stage I bladder cancer?
Transurethral resection of bladder with fulguration + intravesical chemo (gemcitabine or mitomycin)
What is the treatment for stage II & III bladder cancer?
Neoadjuvant cisplatin
What is the treatment for stage I prostate cancer?
Watchful waiting, possible prostatectomy or cryotherapy
What is the initial treatment for malignant melanoma?
Complete excision with disease free margins
Standard treatment for most early stage head and neck cancers
Surgical resection
What is 1st treatment for neurologic system cancers?
Surgery
What is treatment for CLL?
Watchful waiting
What is the treatment for AML?
Induction: cytarabine and anthracycline
Consolidation: daunorubicin or idarubicin and etoposide
What is the treatment for CML?
Imatinib, dasatinib or nilotinib, allogenic bone marrow transplant or stem cell transplant
What is the treatment for ALL?
Induction and CNS prophylaxis: Imatinib, cyclophosphamide, vincristine, doxorubicin, dex alternated with high dose MTX and cytarabine
What is 1st line treatment for Hodgkin’s lymphoma?
ABVD: adriamycin/doxorubicin, bleomycin, vincristine, dacarbazine)
What risks arise after mantle radiation in teens and young adults?
Increase risk of breast cancer and cardiac toxicity
What targeted therapy is used to treat Non-Hodgkin’s lymphoma?
Rituximab and obinutuzimab
What is the treatment for Ewing sarcoma?
Systemic chemo + RT(if unresectable), surgery (is resectable) or both
Doxorubicin, ifosfamide, etoposide, cyclophosphamide, vincristine
Stem cell transplant is high risk for relapse
What can help avoid amputation in soft tissue sarcoma?
Pre and post-op radiation decreases the risk of local recurrence
What is treatment for Kaposi sarcoma?
Antiretroviral therapy (ART)
If advanced or not responding, chemo or RT
What are the potential side effects of radiation?
Nausea, appetite changes, diarrhea, fatigue, leukopenia, thrombocytopenia
What is the most appropriate vascular access device for an AML for pt going through induction therapy?
Port
Minimize radiation exposure
Type of radiation source
As Low As Reasonably Achievable
Lead shielding (or plexiglass for beta particles)
Time exposed
Distance from radiation source: double the distance between you and source