Treating Tobacco Use Disorder and Managing Other Toxic Exposures Flashcards

1
Q

What is the single largest preventable cause of morbidity and mortality in the US?

A

Tobacco

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Smokers have a life expectancy at least home years shorter than for non smokers?

A

10 year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How many deaths annually are due to smoking?

A

480,000- this includes deaths from second hand smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The greatest annual mortality numbers in the US related to smoking are caused by what?

A

cancer
cardiovascular disease
respiratory disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

List 13 health risks of smoking

A
  1. Diabetes ( smokers are at 30-40% increased risk of developing diabetes compared to nonsmokers)
  2. Rheumatoid arthritis
  3. impaired immune system/immune function, due to high levels of tar
  4. Reduced quality of life
  5. problems with reproduction in men and women
  6. poorer quality, slower wound healing
  7. TB
  8. ectopic pregnancy, preterm delivery, stillbirth, low birth weight, SIDS
  9. cleft lip and cleft palate
  10. ED
  11. age- related macular degeneration
  12. failure rate of treatment for all cancers
  13. bone fractures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common form of chemical dependence in the US?

A

Nicotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What % of smokers desire to quit?

A

70%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which cancers have the clearest link to alcohol use?

A

head and neck
esophagus
liver
breast
colon/rectum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What can excessive alcohol use increase the risk of?

A

high blood pressure
stroke
unintentional injuries
OB complications

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does the USPHS recommend when it comes to screening for tobacco use?

A

1.Clinicians need to recognize that tobacco dependence is a chronic disease and should be treated appropriately.
2. should consistently assess and document tobacco use
3.tobacco use treatments are effective across a broad range of populations
4. brief tobacco dependence treatment is effective
5. individual, group, and telephone counseling is effective
6. if a tobacco user is not ready to quit, clinicians should use MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the criteria for lung cancer screening?

A

greater or equal to 20 pack year smoking hx
current smoker or quit in the last 15 years
btwn the ages of 50-80

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the Fagerstrom Test for Nicotine Dependence?

A

10 item self-report questionnaire specifically designed to measure tobacco dependence
7-10 high dependence
4-6 moderate dependence
< 4 minimal dependence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the heaviness of Smoking index?

A

It is a 2 question test derived from the Fagerstrom test.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 2 questions on the Heaviness of smoking index?

A
  1. Time to first cigarette after waking
  2. number of cigarettes per day.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is considered a standard drink?

A

14 grams of alcohol
12 oz of 5% alcohol by volume
5 oz of 12 ABV wine
1.5 oz of 40% ABV 80 proof spirits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the recommended limits on drinking?

A

2 or less drinks a day for men and one drink or less a day for women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the definition of binge drinking?

A

drinking enough that BAC increases to 0.08mg/L
typical amounts are 5 drinks in 2 hours for men, 4 drinks in 2 hours for women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is the definition of heavy alcohol use?

A

binge drinking 5 or more drinks on at least 5 days in the past month.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is at risk drinking?

A

1.exceeds the levels above for any day of the week
2.binge drinking at least once a month
3. drinking that increases the risk of future problems, even thought there are no current symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the definition of alcohol use disorder?

A

a pattern of use that leads to impairment or distress
meets at least 2/11 criteria for a substance use disorder

20
Q

What are the different screening tools that can be used to screen for unhealthy alcohol use?

A

CAGE
AUDIT
NMASSIST
CRAFFT
TAPS
MSASQ

21
Q

when should ppl be screened for unhealthy alcohol use?

A

Annual prevention examination
family planning visits
prenatal visits
problem oriented visits
high risk groups

22
Q

What health problems does alcohol misuse put patients at?

A

anemia
osteoporosis
cognitive decline
live disease
cardiac disease
HTN

23
Q

What is TAPS?

A

TAPS is an assessment to be administered by the patient or the clinician
TAPS-1 : 4 questions regarding tobacco, alcohol use above the recommended limits, prescription medication in a non-medical fashion and use of illicit substances
TAPS-2: a longer more in depth tool
Has > 70% sensitivity for identifying a substance use disorder at a score of 2 or higher

24
Q

Vareniciline

A
  1. most effective mono-therapy for patients attempting to quit smoking
  2. Acts as a nicotine receptor partial agonist, meaning the medication binds to the same receptors as nicotine but less strongly
    pregnancy category C
25
Q

Bupropion SR

A

inhibits the re-uptake of Norepinephrine and dopamine at the nerve synapse so that norephrine and dopamine are available to attach to the corresponding receptors and stimulate the postsynaptic neuron
pregnancy category C

26
Q

second line medications for tobacco cessation

A

clonidine and nortriptyline

27
Q

Contraindications to Bupropion

A

use of MAOIs
seizure disorder
bulimia/anorexia
abrupt discontinuation of ethanol or sedatives.

28
Q

Contraindications to varenicline

A

known hx of serious hypersensitivity or skin reactions to vareniciline

29
Q

What is considered first line for adolescents trying to quit smoking?

A

Counseling

30
Q

what are treatments that have not demonstrated effectiveness for smoking cessation?

A

acupunture
hypnosis

31
Q

Follow up schedule for someone trying to quit smoking

A

2 weeks prior to quit date
1 week after quit date
3 months after quit date
6 months after quit date

32
Q

what are medications available for alcohol use?

A

Naltrexon
Acamprosate
Dilsulfiram

33
Q

Naltrexone

A

50mg PO daily
blocks mu-receptor
can begin during alcohol abstinence or during alcohol use to help modulate use.
meant to be taken daily
modest improvements in relapse, # of drinking days, and alcohol craving

34
Q

Acamprosate

A

modulates glutamate neurotransmission.
2nd line medication due to dosing, 2 tablets 3 times a day
most beneficial when not drinking

35
Q

Disulfiram

A

250mg PO daily
aversion agent.
high rates of noncompliance

36
Q

off label medications for alcohol use

A

gabapentin 300-600mg PO 2-3x/day
Topiramate 100-150 mg PO BID

37
Q

Medications for opioid use

A

naltrexone
Buprenorphine
Methadone

38
Q

Naltrexone when using for opioid use disorder

A

50mg PO daily to transition to naltrexone 380mg injections every 4 weeks.
blocks euphoric and sedating effects of opioids, can reduce cravings

39
Q

buprenorphine when using for opioid use disorder

A

partial agonist with high affinity for opioid receptor.
allows mitigation of withdrawal and manages cravings by occupying the opioid receptor.
can precipitate withdrawal if full agonist are present

40
Q

methadone

A

full opioid agonist with long 1/2 life.
must be dispensed through an opioid treatment program when used for opioid use disorder

41
Q

5 As of behavioral change

A

Assess
Advise
Agree
Assist
Arrange

42
Q

5A of tobacco cessation

A

Ask- identify tobacco use and document
Advise- use a clear, strong, and personalized manner when you advise quitting
Assess- is the tobacco user ready to quit
Assist- provide counseling or pharmacotherapy
Arrange- schedule follow-up

43
Q

motivational interviewing to help with tobacco cessation

A

Express empathy- open ended questions, reflective listening, normalize feelings and concerns, support autonomy

Develop discrepancy- highlight discrepancy btwn the patient’s values, goals and priorities, reinforce and support change talk, build and deepen a commitment to change

Roll with resistance: back off and use reflection when the patient expresses resistance, express empathy, as permission to provide information

Support self -efficacy- help the patient build on past successes

44
Q

5Rs of motivational interviewing

A

Relevance: ask the patient to identify the negative consequences of use

Risk of use: acute risks, long-term risks, environmental risks of second hand smoke in spouses

Rewards of quitting: have the patient list potential benefits

Roadblocks to quitting: patient’s identified barriers

Repetition: repeat the steps above at every visit.

45
Q

When to refer to specialist for addition medicine

A

Unsuccessful attempts at moderating substance use
co-occuring psychiatric and physical disorders in which medication choice is complicated
concern for significant withdrawal with cessation or modulation of current use
evaluation for levels of care higher than episodic outpatient visits.

46
Q

Grade A recommendations for tobacco use

A

Providers should ask all adults about tobacco use, advise them to stop using tobacco, and provide behavioral interventions and FDA approved pharmacotherapy for cessation to non-pregnant adults who use tobacco.

provider should ask all pregnant persons about tobacco use, advise them to stop using tobacco, and provide behavioral interventions for cessation to pregnant persons who use tobacco.

47
Q

Grade B recommendations for unhealthy drug use

A

screening should occur by asking questions about unhealthy drug use in adults age 18 and older. it should be implements when services for accurate diagnosis, effective treatment, and appropriate care can be offered or referred.

48
Q

Grade B recommendations for alcohol use

A

clinicians should screen for unhealthy alcohol use in primary care settings in adults 18 and older, including pregnant patients and provider persons engaged in risky or hazardous drinking with brief behavioral counseling interventions to reduce unhealthy alcohol use