Sleep Flashcards
What is first line treatment for insomnia?
CBT
What type of disorders is bright light therapy good for?
circadian and phase shift disorders
what are the components of CBT for insomnia?
sleep hygiene, stimulus control, sleep restriction, cognitive therapy and relaxation therapy
what is stimulus control in regards to sleep?
stimulus control seeks to reassociate lying in bed with sleep.
what is sleep hygiene?
focuses on healthy sleep practices
what is considered the body’s master clock?
the suprachiasmatic nucleus (SCN)
What are physiologic changes induced by healthy sleep?
Lower cortisol and glucose
greater insulin sensitivity
higher daytime leptin and reduced food seeking behaviors
how does healthy sleep impact cardiovascular disorders?
lower sympathetic tone and bp
greater nighttime peripheral perfusion and core body temp cooling
increased stamina and faster cardiovascular recovery time
What are short duration and disrupted sleep correlated with metabolic disorders?
elevated BMI
Obesity (2 fold increased risk)
metabolic syndrome
type 2 diabetes
cardiovascular risk and mortality
How does impaired sleep and/or short sleep duration effect cardiovascular disorders?
elevated sympathetic tone
endothelial injury
dyslipidemia
elevated BP
reduced nighttime peripheral perfusion
increased nighttime core body temp
refractory hypertension
increased heart attacks
increased risk of cardiovascular disease deaths
How does impaired sleep quality and short sleep effect mood and cognition?
Less REM sleep
reduced BNF
impaired learning and memory
emotional distress, imparied moral judgement, and misinterpretation of social cues
decreased alertness and cognitive processing speed
diminished extinguishing of fear
What behavioral health disorders are short sleep correlated with?
major depression
bipolar disorder
seasonal affective disorder
premenstrual syndrome
worsened PTSD, if the sleep deprivation occurs 2 weeks prior to the traumatic event
Worsened TBI if the sleep deprivation occurs before and/or following the injury
Which cancers are sleep disruption and short sleep duration correlated with?
breast, endometrial, prostate, colorectal and acute myeloid leukemia
When should you order a sleep study?
order a sleep study if you suspect breathing related sleep disorder, narcolepsy, nocturnal seizures, periodic limb movement disorder, REM sleep behavior disorder
What phase of sleep is characterized by sleep spindles and k-complexes?
NREM stage 2, spend about 50% of the night in this phase
What phase of sleep is characterized by slow brain waves
NREM stage 1, usually only experience this at the very beginning of the night
what stage of sleep is called slow wave or deep sleep?
NREM stage 3. 20-25% of the night.
see slow delta waves on EEG
most occurs during the first 1/2 of the night.
What 2 things is deep sleep important for?
- short and long term memories
- restoration of the body, boosting immune system and resorting bones, muscles and tissues
Describes what happens during REM sleep.
20-25% of the night is in REM sleep
first REM occurs about 90-120 minutes after sleep onset
majority of REM occurs during the 2nd half of the night.
What is REM sleep important for?
memory consolidation and promotes brain development.
what are the 4 measures that can be recorded with at home sleep study?
respiratory movement and airflow, heart rate or echocardiogram
arterial oxygen saturation
What is actigraph?
it is a type of accelerometer intended to approximate sleep via algorithms that log physical activity and then estimate sleep.
Gold standard measure of sleep
can over-estimate sleep